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DTSTART;TZID=Europe/Berlin:20250312T160000
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SUMMARY:'Gut\, Liver and Friends' Seminar with Benjamin Ruf
DESCRIPTION:On Wednesday\, 12.03.2025 at 16:00\, Benjamin Ruf\, M.D.\, will be the speaker of our ‘Gut\, Liver and Friends‘ seminar. \nBenjamin Ruf is a physician-scientist focusing on tumor immunology and immunotherapy in gastrointestinal cancers. Benjamin received his M.D. from studies at the University of Tübingen\, King’s College London and the University of Aberdeen. After graduation\, he started residency in Internal Medicine with a focus on Gastroenterology\, Hepatology and Gastro-Oncology at the University Hospital in Tübingen\, Germany. Between 2019-2023 he did postdoctoral studies at the U.S. National Cancer Institute (NCI) with Dr. Tim Greten. Back in Tübingen\, he works as an independent group leader at the M3 Research Institute and the University Hospital Tübingen and tries to better understand how we can use our body’s own immune system to fight cancers. \nIn his lab\, he aims to expand our knowledge of the composition\, phenotype\, and organization of the tumor immune microenvironment (TiME) in gastrointestinal cancers with the goal to ultimately improve patient care. His research is located at an exciting interface between basic immunology\, translational and clinical research. He uses clinical data to guide our research focus\, he uses systems biology approaches to build hypotheses and then test these hypotheses in functional in vivo and in vitro models. He employs complementary experimental strategies to investigate the TiME in patient samples including scRNA-seq\, spatial proteomics and high-dimensional spectral cytometry. Using these approaches\, he studies how reciprocal communications between the innate and adaptive immune system\, stomal cells and cancer cells are altered in response to tumor initiation\, progression\, and response to (immuno)therapy. One focus of his research program is to investigate the role of tissue-resident lymphocytes\, in particular mucosal-associated invariant T (MAIT) cells\, in the context of cancer. Beyond that and following up on previous studies\, he continues to explore how the liver as a site of primary tumorigenesis or metastasis represents a unique tumor microenvironment that requires special consideration. \nHis talk will be entitled: \n“Targeting Mucosal-Associated Invariant T (MAIT) cells in liver cancer – using functional in situ phenotyping to guide precision immunotherapy”.
URL:https://www.crc1382.org/event/gut-liver-and-friends-seminar-with-benjamin-ruf/
LOCATION:online
CATEGORIES:Gut, Liver and Friends Seminar
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DTSTART;TZID=Europe/Berlin:20250319T123000
DTEND;TZID=Europe/Berlin:20250319T140000
DTSTAMP:20250203T075959Z
CREATED:20240819T103841Z
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SUMMARY:'Gut\, Liver and Friends' Seminar with Lindsey Devisscher
DESCRIPTION:On Wednesday\, 19.03.2025 at 12:30\, Prof. Lindsey Devisscher will be the speaker of our ‘Gut\, Liver and Friends‘ seminar. \nProf. Lindsey Devisscher is PI of the Gut-Liver ImmunoPharmacology (GLIPh) unit at the Dpt. of Basic and Applied Medical Sciences of the Faculty of Medicine and Health Sciences of the University of Ghent. She has a master’s degree in veterinary medicine\, performed her PhD on inflammatory bowel diseases and continued her scientific career as postdoctoral scientist with focus on liver disease. She was appointed professor in 2018 and founded the GLIPh unit\, which further builds on her expertise and focusses on the pathogenesis and new therapeutic options for gastro-intestinal related liver diseases with emphasize on the gut-liver axis and innate immunity. Prof. Devisscher is highly experienced in animal models for gut and liver pathology\, is chair of the Animal Ethics Committee of her faculty and attaches great importance to the translational value of experimental models. In line\, her research has a fundamental and translational approach by using relevant animal models\, and linking results to data retrieved from human patient samples. Within her University\, she is team lead of the Research Task Force within her department\, member of the Commission for Scientific Research of her faculty and leader of the Core Facility ‘Histology’ of her faculty. In addition to her scientific and institutional leadership\, she lectures pharmacology to medical\, biomedical and pharmacy students and gastro-intestinal physiology to medical students which keeps her up to date within the field of disease pathogenesis and therapy. \nHer talk will be entitled: \n“Gut-liver axis and immune dysregulation in PSC”.
URL:https://www.crc1382.org/event/gut-liver-and-friends-seminar-with-lindsey-devisscher/
LOCATION:online
CATEGORIES:Gut, Liver and Friends Seminar
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