BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//CRC1382 - ECPv6.17.2//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-ORIGINAL-URL:https://www.crc1382.org
X-WR-CALDESC:Events for CRC1382
REFRESH-INTERVAL;VALUE=DURATION:PT1H
X-Robots-Tag:noindex
X-PUBLISHED-TTL:PT1H
BEGIN:VTIMEZONE
TZID:Europe/Berlin
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20240331T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20241027T010000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20250330T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20251026T010000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20260329T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20261025T010000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20270328T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20271031T010000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20250507T123000
DTEND;TZID=Europe/Berlin:20250507T140000
DTSTAMP:20250505T094602Z
CREATED:20250320T095155Z
LAST-MODIFIED:20250505T094602Z
UID:8119-1746621000-1746626400@www.crc1382.org
SUMMARY:'Gut\, Liver and Friends' Seminar with Charlotte Scott
DESCRIPTION:On Wednesday\, 07.05.2025 at 12:30\, Charlotte Scott from VIB-UGent Center for Inflammation Research\, Belgium\, will be the speaker of our ‘Gut\, Liver and Friends‘ seminar. \nThe title of her presentation is: \n“Investigating hepatic macrophage heterogeneity in health and disease“
URL:https://www.crc1382.org/event/gut-liver-and-friends-seminar-with-charlotte-scott/
LOCATION:Lecture Hall 6\, UK Aachen\, Pauwelsstr. 30\, Aachen\, 52074
CATEGORIES:Gut, Liver and Friends Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20250521T123000
DTEND;TZID=Europe/Berlin:20250521T140000
DTSTAMP:20250513T150613Z
CREATED:20250513T150613Z
LAST-MODIFIED:20250513T150613Z
UID:8204-1747830600-1747836000@www.crc1382.org
SUMMARY:'Gut\, Liver and Friends' Seminar with Matthew Mangan
DESCRIPTION:On Wednesday\, 21.05.2025 at 12:30\, Matthew Mangan from the Institute of Medical Microbiology at Cologne University Hospital will be the speaker of our ‘Gut\, Liver and Friends‘ seminar. \nThe title of his presentation is: \n“Cytosolic sodium accumulation is a common danger signal triggering endocytic dysfunction and NLRP3 inflammasome activation“ \n\nDetecting noxious molecules within the endo/lysosomal system is essential for maintaining cellular integrity. Here\, we identify acute cytosolic sodium accumulation as a key trigger for NLRP3 inflammasome activation. Large clostridial toxins\, as well as monosodium urate and silica crystals\, rapidly elevate cytosolic sodium by promoting its release from the endo/lysosomal system\, triggering potassium efflux and subsequent extracellular sodium influx. This rise in cytosolic sodium disrupts endocytic trafficking by collapsing the sodium gradient across endosomal membranes\, leading to peripheral redistribution and activation of NLRP3. Importantly\, non-particulate stimuli\, including nigericin\, also activate NLRP3 by this sodium-dependent mechanism. These findings position cytosolic sodium as a key downstream effector of potassium efflux and a central signal for NLRP3 activation across diverse stimuli.
URL:https://www.crc1382.org/event/gut-liver-and-friends-seminar-with-matthew-mangan/
LOCATION:Lecture Hall 6\, UK Aachen\, Pauwelsstr. 30\, Aachen\, 52074
CATEGORIES:Gut, Liver and Friends Seminar
ORGANIZER;CN="Joel Selkrig":MAILTO:jselkrig@ukaachen.de
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20250625T123000
DTEND;TZID=Europe/Berlin:20250625T140000
DTSTAMP:20250602T110928Z
CREATED:20250602T110928Z
LAST-MODIFIED:20250602T110928Z
UID:8308-1750854600-1750860000@www.crc1382.org
SUMMARY:'Gut\, Liver and Friends' Seminar with David Berry
DESCRIPTION:On Wednesday\, 25.06.2025 at 12:30\, David Berry will be the speaker of our ‘Gut\, Liver and Friends‘ seminar. \nMore information will follow soon.
URL:https://www.crc1382.org/event/gut-liver-and-friends-seminar-with-david-berry/
LOCATION:lecture hall 1\, UKA\, UKA\, Pauwelsstr. 30\, Aachen\, 52074\, Germany
CATEGORIES:Gut, Liver and Friends Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20250702T123000
DTEND;TZID=Europe/Berlin:20250702T140000
DTSTAMP:20250127T101137Z
CREATED:20250127T100902Z
LAST-MODIFIED:20250127T101137Z
UID:8060-1751459400-1751464800@www.crc1382.org
SUMMARY:'Gut\, Liver and Friends' Seminar with Laura J. Pallett
DESCRIPTION:On Wednesday\, 02.07.2025 at 12:30\, Associate Professor Laura J. Pallett will be the speaker of our ‘Gut\, Liver and Friends‘ seminar. \nMore information will follow soon.
URL:https://www.crc1382.org/event/gut-liver-and-friends-seminar-with-laura-pallet/
LOCATION:lecture hall 1\, UKA\, UKA\, Pauwelsstr. 30\, Aachen\, 52074\, Germany
CATEGORIES:Gut, Liver and Friends Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20250709T123000
DTEND;TZID=Europe/Berlin:20250709T140000
DTSTAMP:20250422T075431Z
CREATED:20250422T075431Z
LAST-MODIFIED:20250422T075431Z
UID:8174-1752064200-1752069600@www.crc1382.org
SUMMARY:'Gut\, Liver and Friends' Seminar with Detlef Schuppan
DESCRIPTION:On Wednesday\, 09.07.2025 at 12:30\, Professor Dr. Dr. Detlef Schuppan will be the speaker of our ‘Gut\, Liver and Friends‘ seminar. \nMore information will follow soon.
URL:https://www.crc1382.org/event/gut-liver-and-friends-seminar-with-detlef-schuppan/
LOCATION:lecture hall 1\, UKA\, UKA\, Pauwelsstr. 30\, Aachen\, 52074\, Germany
CATEGORIES:Gut, Liver and Friends Seminar
ORGANIZER;CN="Angela Schippers":MAILTO:anschippers@ukaachen.de
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20251029T123000
DTEND;TZID=Europe/Berlin:20251029T140000
DTSTAMP:20251024T145646Z
CREATED:20251024T145646Z
LAST-MODIFIED:20251024T145646Z
UID:8409-1761741000-1761746400@www.crc1382.org
SUMMARY:'Gut\, Liver and Friends' Seminar with Martin Kriegel
DESCRIPTION:Speaker: Prof. Martin Kriegel\, University of Münster\nTitle: Gut microbiota translocation and lymphocyte migration in autoimmunity\nDate: 29.10.2025\, 12:30 pm\nVenue: lecture hall 1 (UKA).\n\nMartin Kriegel is Head of Rheumatology and Clinical Immunology and Head of the Department of Translational Rheumatology and Immunology at the University of Münster and in addition Adjunct Associate Professor of Immunobiology at Yale University. His laboratory investigates host-microbiota interactions in autoimmune diseases by combining human microbiome studies with gnotobiotic models and in vitro approaches\, including organoids. \nMartin Kriegel has published numerous influential publications on the role of the microbiome in autoimmunity. His work encompasses both fundamental mechanisms of microbial immune modulation and translational studies on diseases such as lupus and rheumatoid arthritis.
URL:https://www.crc1382.org/event/gut-liver-and-friends-seminar-with-martin-kriegel/
LOCATION:in presence at UKA\, lecture hall 1\, Pauwelsstr. 30\, Aachen
CATEGORIES:Gut, Liver and Friends Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20251119T123000
DTEND;TZID=Europe/Berlin:20251119T140000
DTSTAMP:20251024T151120Z
CREATED:20251024T151120Z
LAST-MODIFIED:20251024T151120Z
UID:8418-1763555400-1763560800@www.crc1382.org
SUMMARY:'Gut\, Liver and Friends' Seminar with Mercedes Gomez de Agüero Tamargo
DESCRIPTION:Speaker: Mercedes Gomez de Agüero Tamargo\, University of Würzburg\nTitle: Microbial metabolites in the development and maintenance of barrier integrity and tissue healing \nDate: 19.11.2025\, 12:30 pm\nVenue: seminar room at the Institute of Experimental Molecular Imaging (ExMI)\n\nMercedes Gomez de Agüero Tamargo is group leader at the Institute of Systems Immunology at Würzburg University. The Gomez de Agüero Lab studies host-microbial interactions. The focus of the lab is to understand the crosstalk of the microbiota and its products with host cellular networks. Specifically\, the team tries to elucidate which and how specific molecules mediate the effects of the microbiota on a mechanistic level.
URL:https://www.crc1382.org/event/gut-liver-and-friends-seminar-with-mercedes-gomez/
LOCATION:ExMI seminar room\, Forckenbeckstr. 55\, Aachen\, 52074
CATEGORIES:Gut, Liver and Friends Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20251210T150000
DTEND;TZID=Europe/Berlin:20251210T160000
DTSTAMP:20251118T164251Z
CREATED:20251118T164125Z
LAST-MODIFIED:20251118T164251Z
UID:8420-1765378800-1765382400@www.crc1382.org
SUMMARY:'Gut\, Liver and Friends' Seminar with Espen Melum
DESCRIPTION:Speaker: Prof. Espen Melum\nTitle: Bile duct disease – discovery using sequencing and understanding using chip\nDate: 10.12.2025\, 15:00 pm\nVenue: on site in Berlin\, online via Zoom\n\n\nIn this talk I will first go through how novel pathways for inflammation in the bile ducts can be uncovered using single-cell/nuclei and spatial sequencing in mouse models and human material. Then I will discuss how organ-on-a-chip technology can potentially be used to understand these and other pathways and also serve as a platform for disease modeling.
URL:https://www.crc1382.org/event/gut-liver-and-friends-seminar-with-espen-melum/
LOCATION:hybrid
CATEGORIES:Gut, Liver and Friends Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20251217T123000
DTEND;TZID=Europe/Berlin:20251217T134500
DTSTAMP:20251121T125434Z
CREATED:20251121T125417Z
LAST-MODIFIED:20251121T125434Z
UID:8510-1765974600-1765979100@www.crc1382.org
SUMMARY:'Gut\, Liver and Friends' Seminar with Matteo Iannacone
DESCRIPTION:Speaker: Prof. Matteo Iannacone\nTitle: Immune Surveillance of the Liver\nDate: 17.12.2025\, 12:30 pm\nVenue: on site in Aachen\, online via Zoom\n\n\nMatteo Iannacone obtained his M.D. degree from the University of Milan\, Italy\, followed by a residency in Internal Medicine and a Ph.D. in Immunology from Vita-Salute San Raffaele University in Milan\, Italy. He trained as a postdoctoral fellow at The Scripps Research Institute\, La Jolla\, CA and at Harvard Medical School\, Boston\, MA. He is currently the Director of the Division of Immunology\, Transplantation and Infectious Diseases\, Professor of Pathology\, and Head of the Dynamics of Immune Responses laboratory at the San Raffaele Scientific Institute and University in Milan\, Italy. \nBy combining cutting-edge in vivo imaging techniques\, single-cell technologies and advanced animal models\, Matteo has made fundamental contributions to our understanding of adaptive immune responses against pathogens and tumors. His work has been published in the most important scientific journals (including Nature\, Cell\, Science\, Immunity\, Nature Medicine\, Nature Immunology) and he holds 14 international patents. He has received numerous awards for his work\, including the Armenise-Harvard Foundation Career Development Award\, an ERC Starting Grant\, the Young Investigator Award from the European Association for the Study of the Liver\, the EMBO Young Investigator Award\, an ERC Consolidator Grant\, the Chiara D’Onofrio Award\, two ERC Proof of Concept Grants\, an ERC Advanced Grant. He is an elected member of the Henry Kunkel Society and of EMBO. He serves as the Editor-in-Chief of European Journal of Immunology and an editorial board member for Science Immunology\, Journal of Experimental Medicine\, The EMBO Journal\, Trends in Immunology\, Current Opinion in Immunology\, hLife\, Virology\, Review Commons and Faculty Opinion. He has published more than 125 papers that received more than 15\,000 citations with an H-index of 59.
URL:https://www.crc1382.org/event/gut-liver-and-friends-seminar-with-matteao-iannacone-2/
CATEGORIES:Gut, Liver and Friends Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20260204T123000
DTEND;TZID=Europe/Berlin:20260204T134500
DTSTAMP:20260714T154117Z
CREATED:20260126T163317Z
LAST-MODIFIED:20260714T154117Z
UID:8842-1770208200-1770212700@www.crc1382.org
SUMMARY:'Gut\, Liver and Friends' Seminar with Mikael Sellin
DESCRIPTION:Speaker: Mikael Sellin\, University of Uppsala\, Sweden\nTitle: Gut Bacterial Infection Mechanisms Resolved by Human Organoid Modelling\nDate: 04..02.2026\, 12:30 pm\nVenue: UKA\, lecture hall 1\n\n\nBacterial gut infections represent a globally prevalent cause of disease. Traditionally\, the bacterium – host cell interactions that underlie disease development have been studied under simplistic experimental settings\, often using tumor-derived cell lines as a proxy for the gut tissue. The Sellin laboratory strives to explain the mechanisms that drive invasive gut bacterial disease – elicited by e.g. Salmonella\, Shigella and related enteropathogens – under more physiologically accurate ex vivo conditions. The group combines bacterial genetics and live-cell imaging with methods to culture and conduct infection experiments in organoid models (enteroids and colonoids) of the intestinal tract. In the seminar\, Mikael will exemplify how this approach enables high-resolution mapping of how enterobacteria attack and spread within the gut epithelium\, and how host responses and therapies may counter this onslaught.
URL:https://www.crc1382.org/event/gut-liver-and-friends-seminar-with-mikael-selin/
LOCATION:in presence at UKA\, lecture hall 1\, Pauwelsstr. 30\, Aachen
CATEGORIES:Gut, Liver and Friends Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20260506T123000
DTEND;TZID=Europe/Berlin:20260506T134500
DTSTAMP:20260714T151704Z
CREATED:20260421T151053Z
LAST-MODIFIED:20260714T151704Z
UID:8836-1778070600-1778075100@www.crc1382.org
SUMMARY:'Gut\, Liver and Friends' Seminar with Christoph Schramm
DESCRIPTION:Speaker: Christoph Schramm\, University Medical Center Hamburg-Eppendorf\, Germany\nTitle: T cells as therapeutic targets in autoimmune liver disease\nDate: 06..05.2026\, 12:30 pm\nVenue: UKA\, lecture hall 1\n\nChristoph Schramm works at the Department of Gastroenterology\, Hepatology with Sections Infectious Diseases and Tropical Medicine\, University Medical Center Hamburg – Eppendorf and leads the Martin Zeitz Centre for Rare Diseases. He is an expert in the field of autoimmune liver diseases and immune regulation. Current projects focus on primary sclerosing cholangitis and autoimmune hepatitis.
URL:https://www.crc1382.org/event/gut-liver-and-friends-seminar-with-christoph-schramm-2/
LOCATION:in presence at UKA\, lecture hall 1\, Pauwelsstr. 30\, Aachen
CATEGORIES:Gut, Liver and Friends Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20260520T123000
DTEND;TZID=Europe/Berlin:20260520T134500
DTSTAMP:20260714T134807Z
CREATED:20260512T133955Z
LAST-MODIFIED:20260714T134807Z
UID:8833-1779280200-1779284700@www.crc1382.org
SUMMARY:'Gut\, Liver and Friends' Seminar with Markus Kleinwietfeld
DESCRIPTION:Speaker: Markus Kleinewietfeld\, University of Hasselt\, Belgium\nTitle: Environmental Modulation of Immunity in Health and Disease\nDate: 20.05.2026\, 12:30 pm\nVenue: UKA\, lecture hall 1\n“Meet the Speaker” session for early career scientists after the seminar
URL:https://www.crc1382.org/event/gut-liver-and-friends-seminar-with-markus-kleinwietfeld/
LOCATION:in presence at UKA\, lecture hall 1\, Pauwelsstr. 30\, Aachen
CATEGORIES:Gut, Liver and Friends Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20260902T123000
DTEND;TZID=Europe/Berlin:20260902T134500
DTSTAMP:20260714T132440Z
CREATED:20260714T132440Z
LAST-MODIFIED:20260714T132440Z
UID:8826-1788352200-1788356700@www.crc1382.org
SUMMARY:'Gut\, Liver and Friends' Seminar with Schalk van der Merwe
DESCRIPTION:Speaker: Schalk van der Merwe\, University Hospital Leuven\nTitle: Macrophages as guardians of the gut liver axis in cirrhosis\nDate: 02.09.2026\, 12:30 pm\nVenue: on site at UKA\, lecture hall to be announced
URL:https://www.crc1382.org/event/gut-liver-and-friends-seminar-with-schalk-van-der-merwe-2/
LOCATION:UKA\, Pauwelsstr. 30\, 52074 Aachen\, Germany
CATEGORIES:Gut, Liver and Friends Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20260909T123000
DTEND;TZID=Europe/Berlin:20260909T134500
DTSTAMP:20260714T131432Z
CREATED:20260714T131432Z
LAST-MODIFIED:20260714T131432Z
UID:8821-1788957000-1788961500@www.crc1382.org
SUMMARY:'Gut\, Liver and Friends' Seminar with Immo Prinz
DESCRIPTION:Speaker: Prof. Immo Prinz\nTitle: TBA\nDate: 09.09.2026\, 12:30 pm\nVenue: on site at UKA\, lecture hall to be announced
URL:https://www.crc1382.org/event/gut-liver-and-friends-seminar-with-immo-prinz/
LOCATION:UKA\, Pauwelsstr. 30\, 52074 Aachen\, Germany
CATEGORIES:Gut, Liver and Friends Seminar
END:VEVENT
END:VCALENDAR