| [1] | J. Trebicka, A. Zarbock,
"Editorial: terlipressin in patients with acute-on-chronic liver failure grade 3—too late?", Alimentary pharmacology & therapeutics, vol. 57, no. 1, 2023, pp. 177–178.
|
| [2] | N. Torow, T. W. Hand and M. W. Hornef,
"Programmed and environmental determinants driving neonatal mucosal immune development", Immunity, vol. 56, no. 3, 2023, pp. 485–499.
|
| [3] | C. Roderburg, S. H. Loosen, M. S. Joerdens, M. Demir, T. Lüdde, K. Kostev,
"Antibiotic therapy is associated with an increased incidence of cancer", Journal of cancer research and clinical oncology, vol. 149, no. 3, 2023, pp. 1285–1293.
|
| [4] | A. Queck, L. Schwierz, W. Gu, P. G. Ferstl, C. Jansen, F. E. Uschner, M. Praktiknjo, J. Chang, M. J. Brol, F. Schepis, M. Merli, C. P. Strassburg, J. Lehmann, C. Meyer, J. Trebicka,
"Targeted decrease of portal hepatic pressure gradient improves ascites control after TIPS", Hepatology, vol. 77, no. 2, 2023, pp. 466–475.
|
| [5] | B. Gurbuz, N. Guldiken, P. Reuken, L. Fu, K. Remih, C. Preisinger, R. Brůha, M. Leníček, J. Petrtýl, J. Reissing, M. Aly, M. Fromme, B. Zhou, I. Karkossa, K. Schubert, M. von Bergen, A. Stallmach, T. Bruns, P. Strnad,
"Biomarkers of hepatocellular synthesis in patients with decompensated cirrhosis", Hepatology international, 2023, pp. 11 Seiten.
|
| [6] | A. Guillot, M. Winkler, M. Silva Afonso, A. Aggarwal, D. Lopez, H. Berger, M. S. Kohlhepp, H. Liu, B. Özdirik, J. Eschrich, J. Ma, M. Peiseler, F. Heymann, S. Pendem, S. Mahadevan, B. Gao, L. Diehl, R. Gupta, F. Tacke,
"Mapping the hepatic immune landscape identifies monocytic macrophages as key drivers of steatohepatitis and cholangiopathy progression", Hepatology, 2023.
|
| [7] | J. Guillaume, A. Leufgen, F. T. Hager, O. Pabst, V. Cerovic,
"MHCII expression on gut macrophages supports T cell homeostasis and is regulated by microbiota and ontogeny", Scientific reports, vol. 13, no. 1, 2023, pp. 1509.
|
| [8] | X. Chang, R. Korenblik, B. Olij, R. R. M. M. Knapen, C. van der Leij, D. Heise, M. den Dulk, U. P. Neumann, F. G. Schaap, R. M. van Dam, S. W. M. Olde Damink,
"Influence of cholestasis on portal vein embolization-induced hypertrophy of the future liver remnant", Langenbeck's archives of surgery, vol. 408, no. 1, 2023, pp. 54.
|
| [9] | G. Wang, L. R. Heij, D. Liu, E. Dahl, S. A. Lang, T. F. Ulmer, T. Lüdde, U. P. Neumann, J. Bednarsch,
"The Role of Single-Nucleotide Polymorphisms in Cholangiocarcinoma: A Systematic Review", Cancers, vol. 14, no. 23, 2022, pp. 5969.
|
| [10] | M. Thamm, S. Rosenhain, K. Leonardic, A. Höfter, F. Kießling, F. Osl, T. Pöschinger, F. Gremse,
"Intrinsic Respiratory Gating for Simultaneous Multi-Mouse μCT Imaging to Assess Liver Tumors", Frontiers in medicine, vol. 9, 2022, pp. 878966.
|
| [11] | P. Strnad, M. Mandorfer, G. Choudhury, W. Griffiths, C. Trautwein, R. Loomba, T. Schluep, T. Chang, M. Yi, B. D. Given, J. C. Hamilton, J. San Martin, J. H. Teckman,
"Fazirsiran for Liver Disease Associated with Alpha 1 -Antitrypsin Deficiency", The New England journal of medicine, vol. 387, no. 6, 2022, pp. 514–524.
|
| [12] | J. Soppert, E. F. Brandt, N. M. Heussen, E. Barzakova, L. M. Blank, L. Küpfer, M. W. Hornef, J. Trebicka, J. Jankowski, M. Berres, H. Noels,
"Blood endotoxin levels as biomarker of non-alcoholic fatty liver disease: a systematic review and meta-analysis", Clinical Gastroenterology and Hepatology, 2022.
|
| [13] | A. R. P. Schneider, C. V. Schneider, K. M. Schneider, V. Baier, S. Schaper, C. Diedrich, K. Coboeken, H. Mayer, W. Gu, J. Trebicka, L. M. Blank, R. Burghaus, J. Lippert, D. J. Rader, C. A. Thaiss, J. Schlender, C. Trautwein, L. Küpfer,
"Early prediction of decompensation ( EPOD ) score: Non‐invasive determination of cirrhosis decompensation risk", Liver international, vol. 42, no. 3, 2022, pp. 640–650.
|
| [14] | D. Schöler, K. Kostev, M. Demir, M. Luedde, M. Konrad, T. Lüdde, C. Roderburg, S. H. Loosen,
"An Elevated FIB-4 Score Is Associated with an Increased Incidence of Depression among Outpatients in Germany", Journal of Clinical Medicine, vol. 11, no. 8, 2022, pp. 2214.
|
| [15] | C. Roderburg, T. Essing, L. Kehmann, S. Krieg, S. Labuhn, J. Kandler, T. Lüdde, S. H. Loosen,
"Current Trends in Inpatient Care and In-Hospital Mortality of Cholangiocarcinoma in Germany: A Systematic Analysis between 2010 and 2019", Cancers, vol. 14, no. 16, 2022, pp. 4038.
|
| [16] | B. Richter, S. Zafarnia, F. Gremse, F. Kießling, H. Scheuerlein, U. Settmacher, U. Dahmen,
"Corrosion Cast and 3D Reconstruction of the Murine Biliary Tree After Biliary Obstruction", Journal of Clinical and Experimental Hepatology, vol. 12, no. 3, 2022, pp. 755–766.
|
| [17] | S. Quickert, S. Würstle, P. A. Reuken, S. Hagel, J. Schneider, R. M. Schmid, S. Neugebauer, A. Stallmach, T. Bruns,
"Real-World Effectiveness of Piperacillin/Tazobactam with and without Linezolid for Spontaneous Bacterial Peritonitis", Digestive diseases, vol. 40, no. 6, 2022, pp. 777–786.
|
| [18] | T. Puengel, S. Lefere, J. Hundertmark, M. Kohlhepp, C. Penners, F. Van de Velde, B. Lapauw, A. Hoorens, L. Devisscher, A. Geerts, S. Boehm, Q. Zhao, J. Krupinski, E. D. Charles, B. Zinker, F. Tacke,
"Combined Therapy with a CCR2/CCR5 Antagonist and FGF21 Analogue Synergizes in Ameliorating Steatohepatitis and Fibrosis", International journal of molecular sciences, vol. 23, no. 12, 2022, pp. 6696.
|
| [19] | T. Puengel, B. Weber, T. Wirtz, L. Buendgens, S. H. Loosen, L. Geisler, B. Özdirik, H. Karim, S. A. Jhaisha, J. F. Brozat, P. Hohlstein, A. Eisert, E. Yagmur, C. Trautwein, F. Tacke, A. Koch,
"Low Serum Levels of Soluble Receptor Activator of Nuclear Factor κ B Ligand (sRANKL) Are Associated with Metabolic Dysregulation and Predict Long-Term Mortality in Critically Ill Patients", Diagnostics, vol. 12, no. 1, 2022, pp. 62.
|
| [20] | K. J. Pedersen, S. Haange, K. Žížalová, A. Viehof, T. Clavel, M. Leniček, B. Engelmann, L. Y. Wick, F. G. Schaap, N. Jehmlich, U. Rolle-Kampczyk, M. von Bergen,
"Eggerthella lenta DSM 2243 Alleviates Bile Acid Stress Response in Clostridium ramosum and Anaerostipes caccae by Transformation of Bile Acids", Microorganisms, vol. 10, no. 10, 2022, pp. 2025.
|
| [21] | O. Pabst, A. Izcue,
"Secretory IgA", Nature reviews / Gastroenterology & hepatology, vol. 19, no. 3, 2022, pp. 149–150.
|
| [22] | S. Murthy, I. Karkossa, C. Schmidt, A. Hoffmann, T. Hagemann, K. Rothe, O. Seifert, U. Anderegg, M. von Bergen, K. Schubert, M. Rossol,
"Danger signal extracellular calcium initiates differentiation of monocytes into SPP1/osteopontin-producing macrophages", Cell death & disease, vol. 13, no. 1, 2022, pp. 53.
|
| [23] | S. H. Loosen, T. F. Ulmer, S. Labuhn, J. Bednarsch, S. Lang, P. H. Alizai, A. T. Schneider, M. Vucur, U. P. Neumann, T. Lüdde, C. Roderburg,
"Serum Levels of CXCL13 Are an Independent Predictor of Survival Following Resection of Biliary Tract Cancer", Cancers, vol. 14, no. 17, 2022, pp. 4073.
|
| [24] | S. H. Loosen, B. O. Jensen, C. Tanislav, T. Lüdde, C. Roderburg, K. Kostev,
"Obesity and lipid metabolism disorders determine the risk for development of long COVID syndrome: a cross-sectional study from 50,402 COVID-19 patients", Infection, vol. 50, no. 5, 2022, pp. 1165–1170.
|
| [25] | S. H. Loosen, T. Essing, M. Jördens, A. Koch, F. Tacke, W. T. Knoefel, J. Bode, C. Roderburg, T. Lüdde,
"Current epidemiological trends and in-hospital mortality of acute pancreatitis in Germany: a systematic analysis of standardized hospital discharge data between 2008 and 2017", Zeitschrift für Gastroenterologie, vol. 60, no. 03, 2022, pp. 310–319.
|
| [26] | S. H. Loosen, C. Roderburg, M. S. Jördens, G. Fluegen, T. Lüdde, K. Kostev,
"Overweight and Obesity Determine the Risk for Gastrointestinal Cancer in a Sex-Dependent Manner: A Retrospective Cohort Study of 287,357 Outpatients in Germany", Cancers, vol. 14, no. 4, 2022, pp. 931.
|
| [27] | S. H. Loosen, D. Schöler, M. Luedde, J. Eschrich, T. Lüdde, K. Kostev, C. Roderburg,
"Differential role of chronic liver diseases on the incidence of cancer: a longitudinal analysis among 248,224 outpatients in Germany", Journal of cancer research and clinical oncology, 2022, pp. 7 Seiten.
|
| [28] | S. H. Loosen, K. Kostev, M. S. Jördens, T. Lüdde, C. Roderburg,
"Overlap between irritable bowel syndrome and common gastrointestinal diagnoses: a retrospective cohort study of 29,553 outpatients in Germany", BMC gastroenterology, vol. 22, no. 1, 2022, pp. 48.
|
| [29] | S. H. Loosen, J. F. Halpaap, S. Labuhn, J. Bednarsch, P. H. Alizai, A. A. Roeth, S. A. Lang, M. Vucur, J. N. Kather, W. T. Knoefel, T. F. Ulmer, U. P. Neumann, C. Roderburg, T. Lüdde,
"Golgi Protein 73 (GP73) Serum Levels Predict Outcome after Resection of Biliary Tract Cancer", Cancers, vol. 14, no. 18, 2022, pp. 4428.
|
| [30] | D. Liu, L. R. Heij, Z. Czigany, E. Dahl, S. A. Lang, T. F. Ulmer, T. Lüdde, U. P. Neumann, J. Bednarsch,
"The role of tumor-infiltrating lymphocytes in cholangiocarcinoma", Journal of experimental & clinical cancer research, vol. 41, no. 1, 2022, pp. 127.
|
| [31] | A. Leufgen, "Intestinal and hepatic dendritic cells in the induction of tolerogenic responses", thesis, RWTH Aachen University, Aachen, 2022.
|
| [32] | I. Labiano, A. Agirre-Lizaso, P. Olaizola, A. Echebarria, M. Huici-Izagirre, I. Olaizola, A. Esparza-Baquer, O. Sharif, E. Hijona, P. Milkiewicz, M. Milkiewicz, F. González-Romero, P. Aspichueta, M. J. Monte, J. J. G. Marin, M. Vucur, T. Lüdde, M. Marzioni, D. A. Mann, L. Bujanda, P. M. Rodrigues, J. M. Banales, M. J. Perugorria,
"TREM-2 plays a protective role in cholestasis by acting as a negative regulator of inflammation", Journal of hepatology, vol. 77, no. 4, 2022, pp. 991–1004.
|
| [33] | S. Krieg, C. Roderburg, A. Krieg, T. Lüdde, S. H. Loosen, K. Kostev,
"The association between body height and cancer: a retrospective analysis of 784,192 outpatients in Germany", Journal of cancer research and clinical oncology, 2022.
|
| [34] | S. Krieg, T. Essing, A. Krieg, C. Roderburg, T. Lüdde, S. H. Loosen,
"Recent Trends and In-Hospital Mortality of Transarterial Chemoembolization (TACE) in Germany: A Systematic Analysis of Hospital Discharge Data between 2010 and 2019", Cancers, vol. 14, no. 9, 2022, pp. 2088.
|
| [35] | M. Kleinjans, C. V. Schneider, T. Bruns, P. Strnad,
"Phenome of coeliac disease vs. inflammatory bowel disease", Scientific reports, vol. 12, 2022, pp. 14572.
|
| [36] | J. Hundertmark, H. Berger and F. Tacke, Single Cell RNA Sequencing in NASH, New York, NY: Humana Press, 2022, pp. 181–202.
|
| [37] | S. Haange, A. Till, P. Bergh, G. Fauler, M. Gigl, A. Löfgren-Sandblom, F. G. Schaap, T. Clavel, C. Trautwein, W. Fenske, K. Kleigrewe, H. Marschall, S. W. M. Olde Damink, T. Moustafa, M. von Bergen, U. Rolle-Kampczyk,
"Ring Trial on Quantitative Assessment of Bile Acids Reveals a Method- and Analyte-Specific Accuracy and Reproducibility", Metabolites, vol. 12, no. 7, 2022, pp. 583.
|
| [38] | F. Guo, O. Estévez-Vázquez, R. Benedé-Ubieto, D. Maya-Miles, K. Zheng, R. Gallego-Durán, . Rojas, J. Ampuero, M. Romero-Gómez, K. Philip, I. U. Egbuniwe, C. Chen, J. Simon, T. C. Delgado, M. L. Martínez-Chantar, J. Sun, J. Reissing, T. Bruns, A. Lamas-Paz, M. G. D. Moral, M. M. Woitok, J. Vaquero, J. R. Regueiro, C. Liedtke, C. Trautwein, R. Bañares, F. J. Cubero, Y. A. Nevzorova,
"A Shortcut from Metabolic-Associated Fatty Liver Disease (MAFLD) to Hepatocellular Carcinoma (HCC): c-MYC a Promising Target for Preventative Strategies and Individualized Therapy", Cancers, vol. 14, no. 1, 2022, pp. 192.
|
| [39] | A. Ghallab, R. Hassan, U. Hofmann, A. Friebel, Z. Hobloss, L. Brackhagen, B. Begher-Tibbe, M. Myllys, J. Reinders, N. Overbeck, S. Sezgin, S. Zühlke, A. Seddek, W. Murad, T. Brecklinghaus, F. Kappenberg, J. Rahnenführer, D. González, C. Goldring, I. M. Copple, R. Marchan, T. Longerich, M. Vucur, T. Lüdde, S. Urban, A. Canbay, T. Schreiter, M. Trauner, J. Y. Akakpo, M. Olyaee, S. C. Curry, J. Sowa, H. Jaeschke, S. Hoehme, J. G. Hengstler,
"Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity", Journal of hepatology, vol. 77, no. 1, 2022, pp. 71–83.
|
| [40] | E. Gardey, F. H. Sobotta, S. Quickert, T. Bruns, J. C. Brendel, A. Stallmach,
"ROS-Sensitive Polymer Micelles for Selective Degradation in Primary Human Monocytes from Patients with Active IBD", Macromolecular bioscience, vol. 22, no. 4, 2022, pp. 2100482.
|
| [41] | C. M. Fries, S. Haange, U. Rolle-Kampczyk, A. Till, M. Lammert, L. Grasser, E. Medawar, A. Dietrich, A. Horstmann, M. von Bergen, W. K. Fenske,
"Metabolic Profile and Metabolite Analyses in Extreme Weight Responders to Gastric Bypass Surgery", Metabolites, vol. 12, no. 5, 2022, pp. 417.
|
| [42] | L. Colyn, G. Alvarez-Sola, M. U. Latasa, I. Uriarte, J. M. Herranz, M. Arechederra, G. Vlachogiannis, C. Rae, A. Pineda-Lucena, A. Casadei-Gardini, F. Pedica, L. Aldrighetti, A. López-López, A. López-Gonzálvez, C. Barbas, S. Ciordia, S. M. Van Liempd, J. M. Falcón-Pérez, J. Urman, B. Sangro, S. Vicent, M. J. Iraburu, F. Prosper, L. J. Nelson, J. M. Banales, M. L. Martinez-Chantar, J. J. G. Marin, C. Braconi, C. Trautwein, F. J. Corrales, F. J. Cubero, C. Berasain, M. G. Fernandez-Barrena, M. A. Avila,
"New molecular mechanisms in cholangiocarcinoma: signals triggering interleukin-6 production in tumor cells and KRAS co-opted epigenetic mediators driving metabolic reprogramming", Journal of experimental & clinical cancer research, vol. 41, 2022, pp. 183.
|
| [43] | T. Clavel, H. Horz, N. Segata, M. J. G. T. Vehreschild,
"Next steps after 15 stimulating years of human gut microbiome research", Microbial biotechnology, vol. 15, no. 1, 2022, pp. 164–175.
|
| [44] | A. Bruneau, A. Guillot and F. Tacke,
"Macrophages in cholangiopathies", Current opinion in gastroenterology, vol. 38, no. 2, 2022, pp. 114–120.
|
| [45] | J. F. Brozat, F. Hanses, M. Haelberger, M. Stecher, M. Dreher, L. Tometten, M. M. Ruethrich, J. J. Vehreschild, C. Trautwein, S. Borgmann, M. J. G. T. Vehreschild, C. E. M. Jakob, A. Stallmach, K. Wille, K. Hellwig, N. Isberner, P. A. Reuken, F. Geisler, J. Nattermann, T. Bruns, L. study group,
"COVID‐19 mortality in cirrhosis is determined by cirrhosis‐associated comorbidities and extrahepatic organ failure: Results from the multinational LEOSS registry", United european gastroenterology journal, vol. 10, no. 4, 2022, pp. 409–424.
|
| [46] | J. F. Brozat, E. F. Brandt, M. Stark, P. Fischer, T. Wirtz, A. Flaßhove, A. N. Rodenhausen, T. Vajen, A. C. A. Heinzmann, S. M. Schmitz, S. Abu Jhaisha, A. A. J. Röth, R. R. Koenen, H. Sahin, C. Trautwein, M. Berres,
"JAM‐A is a multifaceted regulator in hepatic fibrogenesis, supporting LSEC integrity and stellate cell quiescence", Liver international, vol. 42, no. 5, 2022, pp. 1185–1203.
|
| [47] | I. Biancacci, F. De Lorenzi, B. Theek, X. Bai, J. May, L. Consolino, M. Baues, D. Moeckel, F. Gremse, S. Stillfried, A. El Shafei, K. Benderski, A. Azadkhah Shalmani, A. Wang, J. Momoh, Q. Peña, E. M. Buhl, J. F. Buyel, W. Hennink, F. Kießling, J. Metselaar, Y. Shi, T. Lammers,
"Monitoring EPR Effect Dynamics during Nanotaxane Treatment with Theranostic Polymeric Micelles", Advanced science, 2022, pp. 2103745.
|
| [48] | S. Bhargava, E. Merckelbach, H. Noels, A. Vohra, J. Jankowski,
"Homeostasis in the Gut Microbiota in Chronic Kidney Disease", Toxins, vol. 14, no. 10, 2022, pp. 648.
|
| [49] | S. Bellais, M. Nehlich, M. Ania, A. Duquenoy, W. Mazier, G. van den Engh, J. Baijer, N. Treichel, T. Clavel, I. Belotserkovsky, V. Thomas,
"Species-targeted sorting and cultivation of commensal bacteria from the gut microbiome using flow cytometry under anaerobic conditions", Microbiome, vol. 10, no. 1, 2022, pp. 24.
|
| [50] | J. Bednarsch, Z. Czigany, L. R. Heij, I. Amygdalos, D. Heise, P. Bruners, T. F. Ulmer, U. P. Neumann, S. A. Lang,
"The role of re-resection in recurrent hepatocellular carcinoma", Langenbeck's archives of surgery, 2022, pp. 11 Seiten.
|
| [51] | . Ay, M. Lenicek, A. Classen, S. W. M. Olde Damink, C. Bolm, F. G. Schaap,
"New Kids on the Block", Metabolites, vol. 12, no. 2, 2022, pp. 176.
|
| [52] | S. R. Atkinson, M. Aly, K. Remih, L. D. Tyson, N. Guldiken, R. Goldin, A. Quaglia, M. Thursz, P. Strnad,
"Serum keratin 19 (CYFRA21-1) is a prognostic biomarker in severe alcoholic hepatitis", Liver international, vol. 42, no. 5, 2022, pp. 1049–1057.
|
| [53] | A. Afrizal, S. A. V. Jennings, T. C. A. Hitch, T. Riedel, M. Basic, A. Panyot, N. Treichel, F. T. Hager, E. O. Wong, B. Wolter, A. Viehof, A. von Strempel, C. Eberl, E. M. Buhl, B. Abt, A. Bleich, R. H. Tolba, L. M. Blank, W. W. Navarre, F. Kießling, H. Horz, N. Torow, V. Cerovic, B. Stecher, T. Strowig, J. Overmann, T. Clavel,
"Enhanced cultured diversity of the mouse gut microbiota enables custom-made synthetic communities", Cell host and microbe, vol. 30, 2022, pp. S193131282200467X.
|
| [54] | S. Zuo, W. Al Rawashdeh, S. Rosenhain, Z. Magnuska, Y. G. Gyamfuah, F. Kießling, F. Gremse,
"Mixing Matrix-corrected Whole-body Pharmacokinetic Modeling Using Longitudinal Micro-computed Tomography and Fluorescence-mediated Tomography", Molecular imaging & biology, vol. 23, no. 6, 2021, pp. 963–974.
|
| [55] | T. Wirtz, A. Saal, I. Bergmann, P. Fischer, D. Heinrichs, E. F. Brandt, M. T. Koenen, S. Djudjaj, K. M. Schneider, P. Boor, R. Bucala, R. Weiskirchen, J. Bernhagen, C. Trautwein, M. Berres,
"Macrophage migration inhibitory factor exerts pro‐proliferative and anti‐apoptotic effects via CD74 in murine hepatocellular carcinoma", British journal of pharmacology, vol. 178, no. 22, 2021, pp. 4452–4467.
|
| [56] | T. Wirtz, P. A. Reuken, C. Jansen, P. Fischer, I. Bergmann, C. Backhaus, C. Emontzpohl, J. Reißing, E. F. Brandt, M. T. Koenen, K. M. Schneider, R. Schierwagen, M. J. Brol, J. Chang, H. W. Zimmermann, N. Köse-Vogel, T. Eggermann, I. Kurth, C. Stoppe, R. Bucala, J. Bernhagen, M. Praktiknjo, A. Stallmach, C. Trautwein, J. Trebicka, T. Bruns, M. Berres,
"Balance between macrophage migration inhibitory factor and sCD74 predicts outcome in patients with acute decompensation of cirrhosis", JHEP reports, vol. 3, no. 2, 2021, pp. 100221.
|
| [57] | Y. Wen, J. Lambrecht, C. Ju, F. Tacke,
"Hepatic macrophages in liver homeostasis and diseases-diversity, plasticity and therapeutic opportunities", Cellular & molecular immunology, vol. 18, no. 1, 2021, pp. 45–56.
|
| [58] | C. Wagner, N. Torow, M. W. Hornef, H. Lelouard,
"Spatial and temporal key steps in early-life intestinal immune system development and education", The FEBS journal, vol. 289, no. 16, 2021, pp. 4731–4757.
|
| [59] | J. Voss, C. V. Schneider, M. Kleinjans, T. Bruns, C. Trautwein, P. Strnad,
"Hepatobiliary phenotype of individuals with chronic intestinal disorders", Scientific reports, vol. 11, 2021, pp. 19954.
|
| [60] | J. Trebicka, P. Bork, A. Krag, M. Arumugam,
"Utilizing the gut microbiome in decompensated cirrhosis and acute-on-chronic liver failure", Nature reviews / Gastroenterology & hepatology, vol. 18, no. 3, 2021, pp. 167–180.
|
| [61] | J. Trebicka, J. Macnaughtan, B. Schnabl, D. L. Shawcross, J. S. Bajaj,
"The microbiota in cirrhosis and its role in hepatic decompensation", Journal of hepatology, vol. 75, no. Supplement 1, 2021, pp. S67–S81.
|
| [62] | S. Torres, M. J. Brol, F. Magdaleno, R. Schierwagen, F. E. Uschner, S. Klein, C. Ortiz, O. Tyc, N. Bachtler, J. Stunden, D. Bertheloot, A. Kitanovic, B. Sanchez, J. Schrum, W. R. Roush, L. Franchi, K. Byth, E. Latz, J. Trebicka,
"The Specific NLRP3 Antagonist IFM-514 Decreases Fibrosis and Inflammation in Experimental Murine Non-Alcoholic Steatohepatitis", Frontiers in molecular biosciences, vol. 8, 2021, pp. 715765.
|
| [63] | F. Tacke, R. Weiskirchen,
"Non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH)-related liver fibrosis", Annals of translational medicine, vol. 9, no. 8, 2021, pp. 729.
|
| [64] | T. Streidl, I. Karkossa, R. R. Segura Muñoz, C. Eberl, A. Zaufel, J. Plagge, R. Schmaltz, K. Schubert, M. Basic, K. M. Schneider, M. Afify, C. Trautwein, R. H. Tolba, B. Stecher, H. L. Doden, J. M. Ridlon, J. Ecker, T. Moustafa, M. von Bergen, A. E. Ramer-Tait, T. Clavel,
"The gut bacterium Extibacter muris produces secondary bile acids and influences liver physiology in gnotobiotic mice", Gut microbes, vol. 13, no. 1, 2021, pp. 1–21.
|
| [65] | C. Seikrit, O. Pabst,
"The immune landscape of IgA induction in the gut", Seminars in immunopathology, vol. 43, no. 5, 2021, pp. 627–637.
|
| [66] | M. F. Schulze-Hagen, C. Roderburg, T. H. Wirtz, M. S. Jördens, L. Bündgens, S. Abu Jhaisha, P. Hohlstein, J. F. Brozat, P. Bruners, C. Loberg, C. K. Kuhl, C. Trautwein, F. Tacke, T. Lüdde, S. H. Loosen, A. Koch,
"Decreased Bone Mineral Density Is a Predictor of Poor Survival in Critically Ill Patients", Journal of Clinical Medicine, vol. 10, no. 16, 2021, pp. 3741.
|
| [67] | K. Schubert, I. Karkossa, J. Schor, B. Engelmann, L. M. Steinheuer, T. Bruns, U. Rolle-Kampczyk, J. Hackermüller, M. von Bergen,
"A Multi-Omics Analysis of Mucosal-Associated-Invariant T Cells Reveals Key Drivers of Distinct Modes of Activation", Frontiers in immunology, vol. 12, 2021, pp. 616967.
|
| [68] | C. V. Schneider, M. Fromme, K. M. Schneider, T. Bruns, P. Strnad,
"Mortality in Patients With Genetic and Environmental Risk of Liver Disease", The American journal of gastroenterology, vol. 116, no. 8, 2021, pp. 1741–1745.
|
| [69] | K. M. Schneider, C. Elfers, A. Ghallab, C. V. Schneider, E. J. C. Galvez, A. Mohs, W. Gui, L. S. Candels, T. Wirtz, S. Zuehlke, M. Spiteller, M. Myllys, A. Roulet, A. Ouzerdine, B. Lelouvier, K. Kilic, L. Liao, A. Nier, E. Latz, I. Bergheim, C. A. Thaiss, J. G. Hengstler, T. Strowig, C. Trautwein,
"Intestinal Dysbiosis Amplifies Acetaminophen-Induced Acute Liver Injury", Cellular and Molecular Gastroenterology and Hepatology, vol. 11, no. 4, 2021, pp. 909–933.
|
| [70] | C. V. Schneider, M. Kleinjans, M. Fromme, K. M. Schneider, P. Strnad,
"Phenome-wide association study in adult coeliac disease", Alimentary pharmacology & therapeutics, vol. 53, no. 4, 2021, pp. 510–518.
|
| [71] | A. Schippers, J. Hübel, F. Heymann, T. Clahsen, S. Eswaran, S. Schlepütz, R. Püllen, N. Gaßler, K. Tenbrock, F. Tacke, N. Wagner,
"MAdCAM-1/α4β7 Integrin-Mediated Lymphocyte/Endothelium Interactions Exacerbate Acute Immune-Mediated Hepatitis in Mice", Cellular and Molecular Gastroenterology and Hepatology, vol. 11, no. 4, 2021, pp. 1227–1250.el.
|
| [72] | S. Roohani, F. Tacke,
"Liver Injury and the Macrophage Issue", International journal of molecular sciences, vol. 22, no. 14, 2021, pp. 7249.
|
| [73] | B. Rolles, J. Gorgulho, M. Tometten, C. Roderburg, M. Vieri, A. Abels, M. Vucur, F. Heymann, F. Tacke, T. H. Brümmendorf, T. Lüdde, F. Beier, S. H. Loosen,
"Telomere Shortening in Peripheral Leukocytes Is Associated With Poor Survival in Cancer Patients Treated With Immune Checkpoint Inhibitor Therapy", Frontiers in oncology, vol. 11, 2021, pp. 729207.
|
| [74] | C. Roderburg, S. H. Loosen, A. Kunstein, R. Mohr, M. S. Jördens, M. Luedde, K. Kostev, T. Lüdde,
"Cancer Patients Have an Increased Incidence of Dementia: A Retrospective Cohort Study of 185,736 Outpatients in Germany", Cancers, vol. 13, no. 9, 2021, pp. 2027.
|
| [75] | C. Roderburg, S. H. Loosen, J. Bednarsch, P. H. Alizai, A. A. Roeth, S. M. Schmitz, M. Vucur, M. Luedde, P. Paffenholz, F. Tacke, C. Trautwein, T. F. Ulmer, U. P. Neumann, T. Lüdde,
"Levels of Circulating PD-L1 Are Decreased in Patients with Resectable Cholangiocarcinoma", International journal of molecular sciences, vol. 22, no. 12, 2021, pp. 6569.
|
| [76] | S. Reitmeier, T. C. A. Hitch, N. Treichel, N. Fikas, B. Hausmann, A. E. Ramer-Tait, K. Neuhaus, D. Berry, D. Haller, I. Lagkouvardos, T. Clavel,
"Handling of spurious sequences affects the outcome of high-throughput 16S rRNA gene amplicon profiling", ISME communications, vol. 1, 2021, pp. 31.
|
| [77] | A. Queck, F. E. Uschner, P. G. Ferstl, M. Schulz, M. J. Brol, M. Praktiknjo, R. Schierwagen, S. Klein, C. P. Strassburg, C. Meyer, C. Jansen, M. Berres, J. Trebicka,
"Role of circulating angiogenin levels in portal hypertension and TIPS", PLOS ONE, vol. 16, no. 8, 2021, pp. e0256473.
|
| [78] | M. Peiseler, F. Tacke,
"An Unexpected Line of Defense", Hepatology, vol. 74, no. 5, 2021, pp. 2888–2890.
|
| [79] | M. Peiseler, F. Tacke,
"Inflammatory Mechanisms Underlying Nonalcoholic Steatohepatitis and the Transition to Hepatocellular Carcinoma", Cancers, vol. 13, no. 4, 2021, pp. 730.
|
| [80] | H. S. Muti, L. R. Heij, G. Keller, M. Kohlruss, R. Langer, B. Dislich, J. Cheong, Y. Kim, H. Kim, M. Kook, D. Cunningham, W. H. Allum, R. E. Langley, M. G. Nankivell, P. Quirke, J. D. Hayden, N. P. West, A. J. Irvine, T. Yoshikawa, T. Oshima, R. Huss, B. Grosser, F. Roviello, A. d'Ignazio, A. Quaas, H. Alakus, X. Tan, A. T. Pearson, T. Lüdde, M. P. Ebert, D. Jäger, C. Trautwein, N. T. Gaisa, H. I. Grabsch, J. N. Kather,
"Development and validation of deep learning classifiers to detect Epstein-Barr virus and microsatellite instability status in gastric cancer", The lancet / Digital health, vol. 3, no. 10, 2021, pp. e654–e664.
|
| [81] | M. Muschaweck, L. Kopplin, F. Ticconi, A. Schippers, A. Iljazovic, E. J. C. Gálvez, A. T. Abdallah, N. Wagner, I. G. Costa, T. Strowig, O. Pabst,
"Cognate recognition of microbial antigens defines constricted CD4$^{+}$ T cell receptor repertoires in the inflamed colon", Immunity, vol. 54, no. 11, 2021, pp. 2565–2577.e6.
|
| [82] | S. Monteiro, J. Grandt, F. E. Uschner, N. Kimer, J. L. Madsen, R. Schierwagen, S. Klein, C. Welsch, L. Schäfer, C. Jansen, J. Claria, J. Alcaraz-Quiles, V. Arroyo, R. Moreau, J. Fernandez, F. Bendtsen, G. Mehta, L. L. Gluud, S. Møller, M. Praktiknjo, J. Trebicka,
"Differential inflammasome activation predisposes to acute-on-chronic liver failure in human and experimental cirrhosis with and without previous decompensation", Gut, vol. 70, 2021, pp. 379–387.
|
| [83] | K. Müller, H. Honcharova-Biletska, C. Koppe, M. Egger, L. K. Chan, A. T. Schneider, L. Küsgens, F. Böhm, Y. Boege, M. E. Healy, J. Schmitt, S. Comtesse, M. Castoldi, C. Preisinger, M. Szydlowska, E. Focaccia, N. Gaisa, S. H. Loosen, S. Jörs, F. Tacke, C. Roderburg, V. Keitel, J. G. Bode, P. Boor, R. J. Davis, T. Longerich, F. Geisler, M. Heikenwalder, A. Weber, M. Vucur, T. Lüdde,
"JNK signaling prevents biliary cyst formation through a CASPASE-8-dependent function of RIPK1 during aging", Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 12, 2021, pp. e2007194118.
|
| [84] | B. Misselwitz, A. Wyss, T. Raselli, V. Cerovic, A. W. Sailer, N. Krupka, F. Ruiz, C. Pot, O. Pabst,
"The oxysterol receptor GPR183 in inflammatory bowel diseases", British journal of pharmacology, vol. 178, no. 16, 2021, pp. 3140–3156.
|
| [85] | C. Luciani, F. T. Hager, V. Cerovic, H. Lelouard,
"Dendritic cell functions in the inductive and effector sites of intestinal immunity", Mucosal immunology, vol. 15, no. 1, 2021, pp. 40–50.
|
| [86] | S. H. Loosen, P. Paffenholz, T. Lüdde, K. Kostev, C. Roderburg,
"Diverticular disease is associated with an increased incidence rate of depression and anxiety disorders", International journal of colorectal disease, vol. 36, no. 11, 2021, pp. 2437–2443.
|
| [87] | S. H. Loosen, J. Gorgulho, M. S. Jördens, M. Schulze-Hagen, F. Beier, M. Vucur, A. T. Schneider, C. Koppe, A. Mertens, J. N. Kather, F. Tacke, V. Keitel, T. H. Brümmendorf, C. Roderburg, T. Lüdde,
"Serum Levels of Soluble Urokinase Plasminogen Activator Receptor Predict Tumor Response and Outcome to Immune Checkpoint Inhibitor Therapy", Frontiers in oncology, vol. 11, 2021, pp. 646883.
|
| [88] | S. H. Loosen, H. H. Bock, M. Hellmich, W. T. Knoefel, C. Trautwein, V. Keitel, J. G. Bode, U. P. Neumann, T. Lüdde,
"Hospital Mortality and Current Trends in Liver Transplantation in Germany", Deutsches Ärzteblatt international, vol. 118, no. 29/30, 2021, pp. 497–502.
|
| [89] | S. H. Loosen, V. van den Bosch, J. Gorgulho, M. Schulze-Hagen, J. Kandler, M. S. Jördens, F. Tacke, C. Loberg, G. Antoch, T. Brümmendorf, U. P. Neumann, C. K. Kuhl, T. Lüdde, C. Roderburg,
"Progressive Sarcopenia Correlates with Poor Response and Outcome to Immune Checkpoint Inhibitor Therapy", Journal of Clinical Medicine, vol. 10, no. 7, 2021, pp. 1361.
|
| [90] | S. H. Loosen, C. Roderburg, P. H. Alizai, A. A. Roeth, S. M. Schmitz, M. Vucur, M. Luedde, D. Schöler, P. Paffenholz, F. Tacke, C. Trautwein, T. Lüdde, U. P. Neumann, T. F. Ulmer,
"Comparative Analysis of Circulating Biomarkers for Patients Undergoing Resection of Colorectal Liver Metastases", Diagnostics, vol. 11, no. 11, 2021, pp. 1999.
|
| [91] | J. Lambrecht, M. Porsch-Özçürümez, J. Best, F. Jost-Brinkmann, C. Roderburg, M. Demir, F. Tacke, R. Mohr,
"The APAC Score", Journal of Clinical Medicine, vol. 10, no. 15, 2021, pp. 3392.
|
| [92] | J. Lambrecht, F. Tacke,
"Controversies and Opportunities in the Use of Inflammatory Markers for Diagnosis or Risk Prediction in Fatty Liver Disease", Frontiers in immunology, vol. 11, 2021, pp. 634409.
|
| [93] | B. Kurt, L. Bündgens, T. Wirtz, S. H. Loosen, M. Schulze-Hagen, D. Truhn, J. F. Brozat, S. Abu Jhaisha, P. Hohlstein, G. Koek, R. Weiskirchen, C. Trautwein, F. Tacke, K. Hamesch, A. Koch,
"Serum Perilipin 2 (PLIN2) Predicts Multiple Organ Dysfunction in Critically Ill Patients", Biomedicines, vol. 9, no. 9, 2021, pp. 1210.
|
| [94] | N. Kumar, T. C. A. Hitch, D. Haller, I. Lagkouvardos, T. Clavel,
"MiMiC: a bioinformatic approach for generation of synthetic communities from metagenomes", Microbial biotechnology, vol. 14, no. 4, 2021, pp. 1757–1770.
|
| [95] | K. V. K. Koelfat, K. M. C. van Mierlo, T. M. Lodewick, J. G. Bloemen, G. van der Kroft, I. Amygdalos, U. P. Neumann, C. H. C. Dejong, P. L. M. Jansen, S. W. M. Olde Damink, F. G. Schaap,
"Bile Salt and FGF19 Signaling in the Early Phase of Human Liver Regeneration", Hepatology communications, vol. 5, no. 8, 2021, pp. 1400–1411.
|
| [96] | M. S. Jördens, L. Heinrichs, S. H. Loosen, L. Wittig, V. Keitel, D. Schöler, M. Schulze-Hagen, C. Loberg, G. Antoch, W. T. Knoefel, T. Lüdde, G. Fluegen, C. Roderburg,
"Sarcopenia Predicts Cancer Mortality in Male but Not in Female Patients Undergoing Surgery for Cholangiocellular Carcinoma", Cancers / Molecular Diversity Preservation International (MDPI), vol. 13, no. 21, 2021, pp. 5359.
|
| [97] | Y. Iwakiri, J. Trebicka,
"Portal hypertension in cirrhosis", JHEP reports, vol. 3, no. 4, 2021, pp. 100316.
|
| [98] | H. Innes, H. D. Nischalke, I. N. Guha, K. H. Weiss, W. Irving, D. Gotthardt, E. Barnes, J. Fischer, M. A. Ansari, J. Rosendahl, S. Lin, A. Marot, V. Pedergnana, M. Casper, J. Benselin, F. Lammert, J. McLauchlan, P. L. Lutz, V. Hamill, S. Mueller, J. R. Morling, G. Semmler, F. Eyer, J. von Felden, A. Link, A. Vogel, J. U. Marquardt, S. Sulk, J. Trebicka, L. Valenti, C. Datz, T. Reiberger, C. Schafmayer, T. Berg, P. Deltenre, J. Hampe, F. Stickel, S. Buch,
"The rs429358 Locus in Apolipoprotein E Is Associated With Hepatocellular Carcinoma in Patients With Cirrhosis", Hepatology communications, 2021.
|
| [99] | T. C. A. Hitch, T. Riedel, A. Oren, J. Overmann, T. D. Lawley, T. Clavel,
"Automated analysis of genomic sequences facilitates high-throughput and comprehensive description of bacteria", ISME communications, vol. 1, 2021, pp. 16.
|
| [100] | P. Henneke, K. Kierdorf, L. J. Hall, M. Sperandio, M. W. Hornef,
"Perinatal development of innate immune topology", eLife, vol. 10, 2021, pp. e67793.
|
| [101] | D. Heinrichs, E. F. Brandt, P. Fischer, J. Köhncke, T. Wirtz, N. Guldiken, S. Djudjaj, P. Boor, D. C. Kroy, R. Weiskirchen, R. Bucala, H. E. Wasmuth, P. Strnad, C. Trautwein, J. Bernhagen, M. Berres,
"Unexpected Pro-Fibrotic Effect of MIF in Non-Alcoholic Steatohepatitis Is Linked to a Shift in NKT Cell Populations", Cells, vol. 10, no. 2, 2021, pp. 252.
|
| [102] | D. A. Hausen, L. C. Bossert and U. Trautwein-Bruns,
"Aufgaben- und Kompetenzspektrum der Data Stewards an der RWTH Aachen University", Bausteine Forschungsdatenmanagement, vol. 3, 2021, pp. 92–105.
|
| [103] | K. Große, D. Ohm, S. Würstle, J. F. Brozat, R. M. Schmid, C. Trautwein, A. Stallmach, T. Bruns, P. A. Reuken,
"Clinical characteristics and outcome of patients with enterococcal liver abscess", Scientific reports, vol. 11, no. 1, 2021, pp. 22265.
|
| [104] | N. Guldiken, J. Argemi, B. Gurbuz, S. R. Atkinson, M. Oliverius, P. Fila, K. Hamesch, T. Bruns, J. Cabezas, J. J. Lozano, J. Mann, S. Cao, P. Mathurin, V. H. Shah, C. Trautwein, M. R. Thursz, R. Bataller, P. Strnad,
"Serum transferrin as a biomarker of hepatocyte nuclear factor 4 alpha activity and hepatocyte function in liver diseases", BMC medicine, vol. 19, 2021, pp. 39.
|
| [105] | M. Fulde, K. van Vorst, K. Zhang, A. J. Westermann, T. Busche, Y. C. Huei, K. Welitschanski, I. Froh, D. Pägelow, J. Plendl, C. Pfarrer, J. Kalinowski, J. Vogel, P. Valentin-Weigand, M. Hensel, K. Tedin, U. Repnik, M. W. Hornef,
"SPI2 T3SS effectors facilitate enterocyte apical to basolateral transmigration of Salmonella-containing vacuoles in vivo", Gut microbes, vol. 13, no. 1, 2021, pp. 1973836.
|
| [106] | S. Eswaran, A. Babbar, H. K. Drescher, T. C. A. Hitch, T. Clavel, M. Muschaweck, T. Ritz, D. C. Kroy, C. Trautwein, N. Wagner, A. Schippers,
"Upregulation of anti-oxidative stress response improves metabolic changes in l-selectin-deficient mice but does not prevent NAFLD progression or fecal microbiota shifts", International journal of molecular sciences, vol. 22, no. 14, 2021, pp. 7314.
|
| [107] | O. Estévez-Vázquez, R. Benedé-Ubieto, F. Guo, B. Gómez-Santos, P. Aspichueta, J. Reißing, T. Bruns, C. Sanz-García, S. Sydor, L. P. Bechmann, E. Maranillo, J. R. Sañudo, M. T. Vázquez, A. Lamas-Paz, L. Morán, M. S. Mazariegos, A. Ciudin, J. M. Pericàs, M. I. Peligros, J. Vaquero, E. Martínez-Naves, C. Liedtke, J. R. Regueiro, C. Trautwein, R. Bañares, F. J. Cubero, Y. A. Nevzorova,
"Fat", Biomedicines, vol. 9, no. 10, 2021, pp. 1289.
|
| [108] | A. Echle, N. T. Rindtorff, T. J. Brinker, T. Lüdde, A. T. Pearson, J. N. Kather,
"Deep learning in cancer pathology: a new generation of clinical biomarkers", British journal of cancer, vol. 124, no. 4, 2021, pp. 686–696.
|
| [109] | K. M. Detjen, R. Otto, Y. Giesecke, L. Geisler, P. Riemer, H. Jann, C. Grötzinger, C. Sers, A. Pascher, T. Lüdde, U. Leser, B. Wiedenmann, M. Sigal, F. Tacke, C. Roderburg, L. Hammerich,
"Elevated Flt3L Predicts Long-Term Survival in Patients with High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms", Cancers, vol. 13, no. 17, 2021, pp. 4463.
|
| [110] | A. Bruneau, J. Hundertmark, A. Guillot, F. Tacke,
"Molecular and Cellular Mediators of the Gut-Liver Axis in the Progression of Liver Diseases", Frontiers in medicine, vol. 8, 2021, pp. 725390.
|
| [111] | R. Benedé-Ubieto, O. Estévez-Vázquez, F. Guo, C. Chen, Y. Singh, H. I. Nakaya, M. Gómez Del Moral, A. Lamas-Paz, L. Morán, N. López-Alcántara, J. Reissing, T. Bruns, M. A. Avila, E. Santamaría, M. S. Mazariegos, M. M. Woitok, U. Haas, K. Zheng, I. Juárez, J. M. Martín-Villa, I. Asensio, J. Vaquero, M. I. Peligros, J. Argemi, R. Bataller, J. Ampuero, M. Romero Gómez, C. Trautwein, C. Liedtke, R. Bañares, F. J. Cubero, Y. A. Nevzorova,
"An Experimental DUAL Model of Advanced Liver Damage", Hepatology communications, vol. 5, no. 6, 2021, pp. 1051–1068.
|
| [112] | J. Bednarsch, Z. Czigany, S. H. Loosen, L. Heij, L. Ruckgaber, H. Maes, J. Krause, M. Reen, B. Toteva, T. Vosdellen, P. Bruners, S. A. Lang, T. F. Ulmer, C. Roderburg, T. Lüdde, U. P. Neumann,
"Perioperative rifaximin is not associated with enhanced functional and volumetric recovery after major liver resection", Scientific reports, vol. 11, no. 1, 2021, pp. 17936.
|
| [113] | V. Baier, O. Clayton, R. Nudischer, H. Cordes, A. R. P. Schneider, C. W. J. Thiel, T. Wittenberger, W. Moritz, L. M. Blank, U. P. Neumann, C. Trautwein, J. Kelm, Y. Schrooders, F. Caiment, H. Gmuender, A. Roth, J. V. Castell, J. Kleinjans, L. O. Küpfer,
"A Model-Based Workflow to Benchmark the Clinical Cholestasis Risk of Drugs", Clinical pharmacology & therapeutics, vol. 110, no. 5, 2021, pp. 1293–1301.
|
| [114] | N. van Best, S. Trepels-Kottek, P. Savelkoul, T. Orlikowsky, M. W. Hornef, J. Penders,
"Influence of probiotic supplementation on the developing microbiota in human preterm neonates", Gut microbes, vol. 12, no. 1, 2020, pp. 1826747.
|
| [115] | N. van Best, U. Rolle-Kampczyk, F. G. Schaap, M. Basic, S. W. M. Olde Damink, A. Bleich, P. Savelkoul, M. von Bergen, J. Penders, M. W. Hornef,
"Bile acids drive the newborn’s gut microbiota maturation", Nature Communications, vol. 11, 2020, pp. 3692.
|
| [116] | J. Zeng-Brouwers, S. Pandey, J. Trebicka, M. Wygrecka, L. Schaefer,
"Communications via the Small Leucine-rich Proteoglycans: Molecular Specificity in Inflammation and Autoimmune Diseases", Journal of histochemistry & cytochemistry, vol. 68, no. 12, 2020, pp. 887–906.
|
| [117] | T. Wirtz, L. Buendgens, R. Weiskirchen, S. H. Loosen, N. Haehnsen, T. Puengel, S. Abu Jhaisha, J. F. Brozat, P. Hohlstein, G. Koek, A. Eisert, R. Mohr, C. Roderburg, T. Lüdde, C. Trautwein, F. Tacke, A. Koch,
"Association of Serum Calprotectin Concentrations with Mortality in Critically Ill and Septic Patients", Diagnostics, vol. 10, no. 11, 2020.
|
| [118] | T. Wirtz, S. H. Loosen, L. Buendgens, B. Kurt, S. Abu Jhaisha, P. Hohlstein, J. F. Brozat, R. Weiskirchen, T. Lüdde, F. Tacke, C. Trautwein, C. Roderburg, A. Koch,
"Low Myostatin Serum Levels Are Associated with Poor Outcome in Critically Ill Patients", Diagnostics, vol. 10, no. 8, 2020.
|
| [119] | S. Torres, Z. Abdullah, M. J. Brol, C. Hellerbrand, M. Fernandez, R. Fiorotto, S. Klein, P. Königshofer, C. Liedtke, S. Lotersztajn, Y. A. Nevzorova, R. Schierwagen, T. Reiberger, F. E. Uschner, F. Tacke, R. Weiskirchen, J. Trebicka,
"Recent Advances in Practical Methods for Liver Cell Biology", International journal of molecular sciences, vol. 21, no. 6, 2020, pp. 2027.
|
| [120] | M. Thiele, M. B. Hugger, Y. Kim, P. Rautou, L. Elkrief, C. Jansen, W. Verlinden, G. Allegretti, M. Israelsen, H. Stefanescu, F. Piscaglia, J. C. García-Pagán, S. Franque, A. Berzigotti, L. Castera, W. K. Jeong, J. Trebicka, A. Krag,
"2D shear wave liver elastography by aixplorer to detect portal hypertension in cirrhosis: an individual patient data meta-analysis", Liver international, vol. 40, no. 6, 2020, pp. 1435–1446.
|
| [121] | K. M. Schwarzkopf, L. Eberle, F. E. Uschner, S. Klein, R. Schierwagen, M. M. Mücke, L. Schaefer, J. Clària, S. Zeuzem, E. Hintermann, U. Christen, C. M. Lange, J. Trebicka, C. Welsch,
"Interleukin-22 in acute-on-chronic liver failure: A matter of ineffective levels, receptor dysregulation or defective signalling?", Journal of hepatology, vol. 73, no. 4, 2020, pp. 980–982.
|
| [122] | R. Schierwagen, P. Dietrich, S. Klein, F. E. Uschner, C. Ortiz, O. Tyc, S. Torres, C. Hellerbrand, T. Sauerbruch, J. Trebicka,
"β-Arrestin2 is increased in liver fibrosis in humans and rodents", Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 44, 2020, pp. 27082–27084.
|
| [123] | R. Schierwagen, F. E. Uschner, C. Ortiz, S. Torres, M. J. Brol, O. Tyc, W. Gu, C. Grimm, S. Zeuzem, A. Plamper, P. Pfeifer, S. Zimmer, C. Welsch, L. Schaefer, K. P. Rheinwalt, J. Clària, V. Arroyo, J. Trebicka, S. Klein,
"The Role of Macrophage-Inducible C-Type Lectin in Different Stages of Chronic Liver Disease", Frontiers in immunology, vol. 11, 2020, pp. 1352.
|
| [124] | C. Roderburg, A. Wree, M. Demir, M. Schmelzle, F. Tacke,
"The role of the innate immune system in the development and treatment of hepatocellular carcinoma", Hepatic Oncology, vol. 7, no. 1, 2020, pp. 11 Seiten.
|
| [125] | A. Riba, K. Hassani, A. Walker, N. van Best, D. von Zeschwitz, T. Anslinger, N. Sillner, S. Rosenhain, D. Eibach, O. Maiga-Ascofaré, U. Rolle-Kampczyk, M. Basic, A. Binz, S. Mocek, B. Sodeik, R. Bauerfeind, A. Mohs, C. Trautwein, F. Kießling, J. May, M. Klingenspor, F. Gremse, P. Schmitt-Kopplin, A. Bleich, N. Torow, M. von Bergen, M. W. Hornef,
"Disturbed gut microbiota and bile homeostasis in Giardia-infected mice contributes to metabolic dysregulation and growth impairment", Science translational medicine, vol. 12, no. 565, 2020, pp. eaay7019.
|
| [126] | K. C. Reimer, A. Wree, C. Roderburg, F. Tacke,
"New drugs for NAFLD", Hepatology international, vol. 14, no. 1, 2020, pp. 8–23.
|
| [127] | A. Queck, H. Bode, F. E. Uschner, M. J. Brol, C. Graf, M. Schulz, C. Jansen, M. Praktiknjo, R. Schierwagen, S. Klein, C. Trautwein, H. E. Wasmuth, M. Berres, J. Trebicka, J. Lehmann,
"Systemic MCP-1 Levels Derive Mainly From Injured Liver and Are Associated With Complications in Cirrhosis", Frontiers in immunology, vol. 11, 2020, pp. 354.
|
| [128] | T. Puengel, F. Tacke,
"Editorial: prevalence, progression rates and mortality predictors of non-alcoholic fatty liver disease reflected by German statutory health insurance data", Alimentary pharmacology & therapeutics, vol. 52, no. 8, 2020, pp. 1412–1413.
|
| [129] | T. Puengel, S. De Vos, J. Hundertmark, M. Kohlhepp, N. Guldiken, P. Pujuguet, M. Auberval, F. Marsais, K. F. Shoji, L. Saniere, C. Trautwein, T. Lüdde, P. Strnad, R. Brys, P. Clément-Lacroix, F. Tacke,
"The Medium-Chain Fatty Acid Receptor GPR84 Mediates Myeloid Cell Infiltration Promoting Steatohepatitis and Fibrosis", Journal of Clinical Medicine, vol. 9, no. 4, 2020, pp. 1140.
|
| [130] | R. Pieper, N. van Best, K. van Vorst, F. Ebner, M. Reissmann, M. W. Hornef, M. Fulde,
"Toward a porcine in vivo model to analyze the pathogenesis of TLR5-dependent enteropathies", Gut microbes, vol. 12, no. 1, 2020, pp. 1782163.
|
| [131] | F. C. Pereira, K. Wasmund, I. Cobankovic, N. Jehmlich, C. W. Herbold, K. S. Lee, B. Sziranyi, C. Vesely, T. Decker, R. Stocker, B. Warth, M. von Bergen, M. Wagner, D. Berry,
"Rational design of a microbial consortium of mucosal sugar utilizers reduces Clostridiodes difficile colonization", Nature Communications, vol. 11, 2020, pp. 5104.
|
| [132] | O. Pabst, E. Slack,
"IgA and the intestinal microbiota", Mucosal immunology, vol. 13, no. 1, 2020, pp. 12–21.
|
| [133] | J. C. Mossanen, T. U. Jansen, J. Pracht, A. Liepelt, L. Bündgens, C. Stoppe, A. Goetzenich, T. Simon, R. Autschbach, G. Marx, F. Tacke,
"Elevated circulating CD14++CD16+ intermediate monocytes are independently associated with extracardiac complications after cardiac surgery", Scientific reports, vol. 10, 2020, pp. 947.
|
| [134] | A. Mendler, A. Pierzchalski, M. Bauer, S. Röder, A. Sattler, M. Standl, M. Borte, M. von Bergen, U. Rolle-Kampczyk, G. Herberth,
"MAIT cell activation in adolescents is impacted by bile acid concentrations and body weight", Clinical and experimental immunology, vol. 200, no. 2, 2020, pp. 199–213.
|
| [135] | I. Lurje, L. Hammerich and F. Tacke,
"Dendritic Cell and T Cell Crosstalk in Liver Fibrogenesis and Hepatocarcinogenesis: Implications for Prevention and Therapy of Liver Cancer", International journal of molecular sciences, vol. 21, no. 19, 2020, pp. 7378.
|
| [136] | A. Liepelt, P. Hohlstein, H. Gussen, J. Xue, A. C. Aschenbrenner, T. Ulas, L. Bündgens, K. T. Warzecha, M. Bartneck, T. Lüdde, C. Trautwein, J. L. Schultze, A. Koch, F. Tacke,
"Differential Gene Expression in Circulating CD14+ Monocytes Indicates the Prognosis of Critically Ill Patients with Sepsis", Journal of Clinical Medicine, vol. 9, no. 1, 2020, pp. 127.
|
| [137] | T. R. Lesker, A. C. Durairaj, E. J. C. Gálvez, I. Lagkouvardos, J. F. Baines, T. Clavel, A. Sczyrba, A. C. McHardy, T. Strowig,
"An Integrated Metagenome Catalog Reveals New Insights into the Murine Gut Microbiome", Cell reports, vol. 30, no. 9, 2020, pp. 2909–2922.e6.
|
| [138] | M. Lenicek, S. W. M. Olde Damink and F. G. Schaap,
"Gut Microbes Take It to the Next Level?", Hepatology, vol. 72, no. 4, 2020, pp. 1483–1485.
|
| [139] | S. Lefere, T. Püngel, J. Hundertmark, C. Penners, A. K. Frank, A. Guillot, K. de Muynck, F. Heymann, V. Adarbes, E. Defrêne, C. Estivalet, A. Geerts, L. Devisscher, G. Wettstein, F. Tacke,
"Differential effects of selective- and pan-PPAR agonists on experimental steatohepatitis and hepatic macrophages", Journal of hepatology, vol. 73, no. 4, 2020, pp. 757–770.
|
| [140] | S. Lefere, L. Devisscher and F. Tacke,
"Targeting CCR2/5 in the treatment of nonalcoholic steatohepatitis (NASH) and fibrosis", Expert opinion on investigational drugs, vol. 29, no. 2, 2020, pp. 89–92.
|
| [141] | J. Lambrecht, L. A. van Grunsven and F. Tacke,
"Current and emerging pharmacotherapeutic interventions for the treatment of liver fibrosis", Expert opinion on pharmacotherapy, vol. 21, no. 13, 2020, pp. 1637–1650.
|
| [142] | A. Lamas-Paz, L. Morán, J. Peng, B. Salinas, N. López-Alcántara, S. Sydor, R. Vilchez-Vargas, I. Asensio, F. Hao, K. Zheng, B. Martín-Adrados, L. Moreno, A. Cogolludo, M. Gómez del Moral, L. Bechmann, E. Martínez-Naves, J. Vaquero, R. Bañares, Y. A. Nevzorova, F. J. Cubero,
"Intestinal Epithelial Cell-Derived Extracellular Vesicles Modulate Hepatic Injury via the Gut-Liver Axis During Acute Alcohol Injury", Frontiers in pharmacology, vol. 11, 2020, pp. 603771.
|
| [143] | L. M. Klein, J. Chang, W. Gu, S. Manekeller, C. Jansen, P. Lingohr, M. Praktiknjo, J. C. Kalf, M. Schulz, U. Spengler, C. Strassburg, A. Cárdenas, V. Arroyo, J. Trebicka,
"The Development and Outcome of Acute-on-Chronic Liver Failure After Surgical Interventions", Liver transplantation, vol. 26, no. 2, 2020, pp. 227–237.
|
| [144] | J. N. Kather, L. R. Heij, H. I. Grabsch, C. Loeffler, A. Echle, H. S. Muti, J. Krause, J. M. Niehues, K. A. J. Sommer, P. Bankhead, L. F. S. Kooreman, J. J. Schulte, N. A. Cipriani, R. D. Buelow, P. Boor, N. Ortiz-Brüchle, A. M. Hanby, V. Speirs, S. Kochanny, A. Patnaik, A. Srisuwananukorn, H. Brenner, M. Hoffmeister, P. A. van den Brandt, D. Jäger, C. Trautwein, A. T. Pearson, T. Lüdde,
"Pan-cancer image-based detection of clinically actionable genetic alterations", Nature cancer, vol. 1, no. 8, 2020, pp. 789–799.
|
| [145] | J. Kabbert, J. Benckert, T. Rollenske, T. C. A. Hitch, T. Clavel, V. Cerovic, H. Wardemann, O. Pabst,
"High microbiota reactivity of adult human intestinal IgA requires somatic mutations", Journal of experimental medicine, vol. 217, no. 11, 2020, pp. e20200275.
|
| [146] | J. Hundertmark, F. Tacke,
"How effective are nonalcoholic fatty liver disease models for drug discovery?", Expert opinion on drug discovery, vol. 15, no. 11, 2020, pp. 1237–1240.
|
| [147] | M. W. Hornef, N. Torow,
"‘Layered immunity’ and the ‘neonatal window of opportunity’ - timed succession of non-redundant phases to establish mucosal host-microbial homeostasis after birth", Immunology, vol. 159, no. 1, 2020, pp. 15–25.
|
| [148] | J. Holmar, S. de la Puente-Secades, J. Floege, H. Noels, J. Jankowski, S. Orth-Alampour,
"Uremic Toxins Affecting Cardiovascular Calcification: A Systematic Review", Cells, vol. 9, no. 11, 2020, pp. 2428.
|
| [149] | A. Guillot, M. S. Kohlhepp, A. Bruneau, F. Heymann, F. Tacke,
"Deciphering the Immune Microenvironment on A Single Archival Formalin-Fixed Paraffin-Embedded Tissue Section by An Immediately Implementable Multiplex Fluorescence Immunostaining Protocol", Cancers, vol. 12, no. 9, 2020, pp. 2449.
|
| [150] | A. Guillot, F. Tacke,
"The Unexpected Role of Neutrophils for Resolving Liver Inflammation by Transmitting MicroRNA‐223 to Macrophages", Hepatology, vol. 71, no. 2, 2020, pp. 749–751.
|
| [151] | S. C. Ganal-Vonarburg, M. W. Hornef and A. J. Macpherson,
"Microbial-host molecular exchange and its functional consequences in early mammalian life", Science / Science now, vol. 368, no. 6491, 2020, pp. 604–607.
|
| [152] | A. Echle, H. I. Grabsch, P. Quirke, P. A. van den Brandt, N. P. West, G. G. A. Hutchins, L. R. Heij, X. Tan, S. D. Richman, J. Krause, E. Alwers, J. Jenniskens, K. Offermans, R. Gray, H. Brenner, J. Chang-Claude, C. Trautwein, A. T. Pearson, P. Boor, T. Lüdde, N. T. Gaisa, M. Hoffmeister, J. N. Kather,
"Clinical-Grade Detection of Microsatellite Instability in Colorectal Tumors by Deep Learning", Gastroenterology, vol. 159, no. 4, 2020, pp. 1406–1416.e11.
|
| [153] | H. K. Drescher, A. Schippers, S. Rosenhain, F. Gremse, L. Bongiovanni, A. de Bruin, S. Eswaran, S. U. Gallage, D. Pfister, M. Szydlowska, M. Heikenwalder, S. Weiskirchen, N. Wagner, C. Trautwein, R. Weiskirchen, D. C. Kroy,
"L-Selectin/CD62L is a Key Driver of Non-Alcoholic Steatohepatitis in Mice and Men", Cells, vol. 9, no. 5, 2020, pp. 1106.
|
| [154] | C. Cremonese, R. Schierwagen, F. E. Uschner, S. Torres, O. Tyc, C. Ortiz, M. Schulz, A. Queck, G. Kristiansen, M. Bader, T. Sauerbruch, R. Weiskirchen, T. Walther, J. Trebicka, S. Klein,
"Short-Term Western Diet Aggravates Non-Alcoholic Fatty Liver Disease (NAFLD) With Portal Hypertension in TGR(mREN2)27 Rats", International journal of molecular sciences, vol. 21, no. 9, 2020, pp. 3308.
|
| [155] | L. Buendgens, E. Yagmur, A. Ginsberg, R. Weiskirchen, T. Wirtz, S. A. Jhaisha, A. Eisert, T. Lüdde, C. Trautwein, F. Tacke, A. Koch,
"Midregional Proadrenomedullin (MRproADM) Serum Levels in Critically Ill Patients Are Associated with Short-Term and Overall Mortality during a Two-Year Follow-Up", Mediators of inflammation, vol. 2020, 2020, pp. 7184803.
|
| [156] | L. C. Bossert,
"Mit »biber –tool« Bibliografieeinträge bearbeiten", Die TEXnische Komödie, vol. 2, 2020, pp. 24–33.
|
| [157] | I. Biancacci, Q. Sun, D. Möckel, F. Gremse, S. Rosenhain, F. Kießling, M. Bartneck, Q. Hu, M. Thewissen, G. Storm, W. E. Hennink, Y. Shi, C. J. F. Rijcken, T. Lammers, A. M. Sofias,
"Optical imaging of the whole-body to cellular biodistribution of clinical-stage PEG-b-pHPMA-based core-crosslinked polymeric micelles", Journal of controlled release, vol. 328, 2020, pp. 805–816.
|
| [158] | F. Benz, A. Bogen, M. Praktiknjo, C. Jansen, C. Meyer, A. Wree, M. Demir, S. Loosen, M. Vucur, R. Schierwagen, F. Tacke, J. Trebicka, C. Roderburg,
"Serum levels of bone sialoprotein correlate with portal pressure in patients with liver cirrhosis", PLOS ONE, vol. 15, no. 4, 2020, pp. e0231701.
|
| [159] | M. Bartneck, C. Koppe, V. Fech, K. T. Warzecha, M. Kohlhepp, S. Huss, R. Weiskirchen, C. Trautwein, T. Lüdde, F. Tacke,
"Roles of CCR2 and CCR5 for Hepatic Macrophage Polarization in Mice With Liver Parenchymal Cell-Specific NEMO Deletion", Cellular and Molecular Gastroenterology and Hepatology, vol. 11, no. 2, 2020, pp. 327–347.
|
| [160] | S. Sutti, S. Bruzzì, F. Heymann, A. Liepelt, O. Krenkel, A. Toscani, N. Ramavath, D. Cotella, E. Albano, F. Tacke,
"CX3CR1 Mediates the Development of Monocyte-Derived Dendritic Cells during Hepatic Inflammation", Cells, vol. 8, no. 9, 2019, pp. 1099.
|
| [161] | A. Queck, D. Thomas, C. Jansen, Y. Schreiber, S. Rüschenbaum, M. Praktiknjo, K. M. Schwarzkopf, M. M. Mücke, R. Schierwagen, F. E. Uschner, C. Meyer, J. Clària, S. Zeuzem, G. Geisslinger, J. Trebicka, C. M. Lange,
"Pathophysiological role of prostanoids in coagulation of the portal venous system in liver cirrhosis", PLOS ONE, vol. 14, no. 10, 2019, pp. e0222840.
|
| [162] | S. Loosen, M. F. Schulze-Hagen, P. Bruners, F. Tacke, C. Trautwein, C. K. Kuhl, T. Lüdde, C. Roderburg,
"Sarcopenia Is a Negative Prognostic Factor in Patients Undergoing Transarterial Chemoembolization (TACE) for Hepatic Malignancies", Cancers, vol. 11, no. 10, 2019, pp. 1503.
|
| [163] | G. Desalegn, O. Pabst,
"Inflammation triggers immediate rather than progressive changes in monocyte differentiation in the small intestine", Nature Communications, vol. 10, 2019, pp. 3229.
|
| [164] | G. Cullaro, R. Sharma, J. Trebicka, A. Cárdenas, E. C. Verna,
"Precipitants of Acute-on-Chronic Liver Failure: An Opportunity for Preventative Measures to Improve Outcomes", Liver transplantation, vol. 26, no. 2, 2019, pp. 283–293.
|
| [165] | A. Babbar, T. C. A. Hitch, O. Pabst, T. Clavel, J. Hübel, S. Eswaran, N. Wagner, A. Schippers,
"The Compromised Mucosal Immune System of β7 Integrin-Deficient Mice Has Only Minor Effects on the Fecal Microbiota in Homeostasis", Frontiers in microbiology, vol. 10, 2019, pp. 2284.
|