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[1]C. W. J. Thiel, I. Smit, V. Baier, H. Cordes, B. Fabry, L. M. Blank, L. Küpfer,
"Using quantitative systems pharmacology to evaluate the drug efficacy of COX-2 and 5-LOX inhibitors in therapeutic situations", npj Systems biology and applications, vol. 4, no. 1, 2018, pp. 28.
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[2]H. Cordes, C. W. J. Thiel, V. Baier, L. M. Blank, L. Küpfer,
"Integration of genome-scale metabolic networks into whole-body PBPK models shows phenotype-specific cases of drug-induced metabolic perturbation", npj Systems biology and applications, vol. 4, no. 1, 2018, pp. 10.
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[3]C. W. J. Thiel, H. Cordes, I. Conde, J. V. Castell, L. M. Blank, L. Küpfer,
"Model-based contextualization of in vitro toxicity data quantitatively predicts in vivo drug response in patients", Archives of toxicology, vol. 91, no. 2, 2017, pp. 865–883.
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[4]C. W. J. Thiel, H. Cordes, V. Baier, L. M. Blank, L. Küpfer,
"Multiscale modeling reveals inhibitory and stimulatory effects of caffeine on acetaminophen-induced toxicity in humans", CPT: Pharmacometrics & Systems Pharmacology, vol. 6, no. 2, 2017, pp. 136–146.
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[5]M. Lehnen, B. E. Ebert and L. M. Blank,
"A comprehensive evaluation of constraining amino acid biosynthesis in compartmented models for metabolic flux analysis", Metabolic engineering communications, vol. 5, 2017, pp. 34–44.
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[6]L. M. Blank,
"Let's talk about flux or the importance of (intracellular) reaction rates", Microbial biotechnology, vol. 10, no. 1, 2017, pp. 28–30.
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[7]B. E. Ebert, A. Lamprecht, B. Steffen, L. M. Blank,
"Flux-P: Automating Metabolic Flux Analysis", Metabolites, vol. 2, no. 4, 2012, pp. 872–890.
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[8]A. Schmid, L. M. Blank,
"Hypothesis-driven omics integration", Nature Chemical Biology, vol. 6, no. 7, 2010, pp. 485–487.
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[9]L. M. Blank, L. Küpfer,
"Metabolic flux distributions: genetic information, computational predictions, and experimental validation", Applied microbiology and biotechnology, vol. 86, no. 5, 2010, pp. 1243–1255.
[bibtex] [url] [doi]
[10]L. Küpfer, U. Sauer and L. M. Blank,
"Metabolic functions of duplicate genes in Saccharomyces cerevisiae", Genome research, vol. 15, no. 10, 2005, pp. 1421–1430.
[bibtex] [url] [doi]