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2019
[46]S. Loosen, M. F. Schulze-Hagen, P. Bruners, F. Tacke, C. Trautwein, C. K. Kuhl, T. Lüdde, C. Roderburg,
"Sarcopenia Is a Negative Prognostic Factor in Patients Undergoing Transarterial Chemoembolization (TACE) for Hepatic Malignancies", Cancers, vol. 11, no. 10, 2019, pp. 1503. [bibtex] [url] [doi]
2020
[45]M. Bartneck, C. Koppe, V. Fech, K. T. Warzecha, M. Kohlhepp, S. Huss, R. Weiskirchen, C. Trautwein, T. Lüdde, F. Tacke,
"Roles of CCR2 and CCR5 for Hepatic Macrophage Polarization in Mice With Liver Parenchymal Cell-Specific NEMO Deletion", Cellular and Molecular Gastroenterology and Hepatology, vol. 11, no. 2, 2020, pp. 327–347. [bibtex] [url] [doi]
[44]L. Buendgens, E. Yagmur, A. Ginsberg, R. Weiskirchen, T. Wirtz, S. A. Jhaisha, A. Eisert, T. Lüdde, C. Trautwein, F. Tacke, A. Koch,
"Midregional Proadrenomedullin (MRproADM) Serum Levels in Critically Ill Patients Are Associated with Short-Term and Overall Mortality during a Two-Year Follow-Up", Mediators of inflammation, vol. 2020, 2020, pp. 7184803. [bibtex] [url] [doi]
[43]A. Echle, H. I. Grabsch, P. Quirke, P. A. van den Brandt, N. P. West, G. G. A. Hutchins, L. R. Heij, X. Tan, S. D. Richman, J. Krause, E. Alwers, J. Jenniskens, K. Offermans, R. Gray, H. Brenner, J. Chang-Claude, C. Trautwein, A. T. Pearson, P. Boor, T. Lüdde, N. T. Gaisa, M. Hoffmeister, J. N. Kather,
"Clinical-Grade Detection of Microsatellite Instability in Colorectal Tumors by Deep Learning", Gastroenterology, vol. 159, no. 4, 2020, pp. 1406–1416.e11. [bibtex] [url] [doi]
[42]J. N. Kather, L. R. Heij, H. I. Grabsch, C. Loeffler, A. Echle, H. S. Muti, J. Krause, J. M. Niehues, K. A. J. Sommer, P. Bankhead, L. F. S. Kooreman, J. J. Schulte, N. A. Cipriani, R. D. Buelow, P. Boor, N. Ortiz-Brüchle, A. M. Hanby, V. Speirs, S. Kochanny, A. Patnaik, A. Srisuwananukorn, H. Brenner, M. Hoffmeister, P. A. van den Brandt, D. Jäger, C. Trautwein, A. T. Pearson, T. Lüdde,
"Pan-cancer image-based detection of clinically actionable genetic alterations", Nature cancer, vol. 1, no. 8, 2020, pp. 789–799. [bibtex] [url] [doi]
[41]A. Liepelt, P. Hohlstein, H. Gussen, J. Xue, A. C. Aschenbrenner, T. Ulas, L. Bündgens, K. T. Warzecha, M. Bartneck, T. Lüdde, C. Trautwein, J. L. Schultze, A. Koch, F. Tacke,
"Differential Gene Expression in Circulating CD14+ Monocytes Indicates the Prognosis of Critically Ill Patients with Sepsis", Journal of Clinical Medicine, vol. 9, no. 1, 2020, pp. 127. [bibtex] [url] [doi]
[40]T. Puengel, S. De Vos, J. Hundertmark, M. Kohlhepp, N. Guldiken, P. Pujuguet, M. Auberval, F. Marsais, K. F. Shoji, L. Saniere, C. Trautwein, T. Lüdde, P. Strnad, R. Brys, P. Clément-Lacroix, F. Tacke,
"The Medium-Chain Fatty Acid Receptor GPR84 Mediates Myeloid Cell Infiltration Promoting Steatohepatitis and Fibrosis", Journal of Clinical Medicine, vol. 9, no. 4, 2020, pp. 1140. [bibtex] [url] [doi]
[39]T. Wirtz, S. H. Loosen, L. Buendgens, B. Kurt, S. Abu Jhaisha, P. Hohlstein, J. F. Brozat, R. Weiskirchen, T. Lüdde, F. Tacke, C. Trautwein, C. Roderburg, A. Koch,
"Low Myostatin Serum Levels Are Associated with Poor Outcome in Critically Ill Patients", Diagnostics, vol. 10, no. 8, 2020. [bibtex] [url] [doi]
[38]T. Wirtz, L. Buendgens, R. Weiskirchen, S. H. Loosen, N. Haehnsen, T. Puengel, S. Abu Jhaisha, J. F. Brozat, P. Hohlstein, G. Koek, A. Eisert, R. Mohr, C. Roderburg, T. Lüdde, C. Trautwein, F. Tacke, A. Koch,
"Association of Serum Calprotectin Concentrations with Mortality in Critically Ill and Septic Patients", Diagnostics, vol. 10, no. 11, 2020. [bibtex] [url] [doi]
2021
[37]V. Baier, O. Clayton, R. Nudischer, H. Cordes, A. R. P. Schneider, C. W. J. Thiel, T. Wittenberger, W. Moritz, L. M. Blank, U. P. Neumann, C. Trautwein, J. Kelm, Y. Schrooders, F. Caiment, H. Gmuender, A. Roth, J. V. Castell, J. Kleinjans, L. O. Küpfer,
"A Model-Based Workflow to Benchmark the Clinical Cholestasis Risk of Drugs", Clinical pharmacology & therapeutics, vol. 110, no. 5, 2021, pp. 1293–1301. [bibtex] [url] [doi]
[36]J. Bednarsch, Z. Czigany, S. H. Loosen, L. Heij, L. Ruckgaber, H. Maes, J. Krause, M. Reen, B. Toteva, T. Vosdellen, P. Bruners, S. A. Lang, T. F. Ulmer, C. Roderburg, T. Lüdde, U. P. Neumann,
"Perioperative rifaximin is not associated with enhanced functional and volumetric recovery after major liver resection", Scientific reports, vol. 11, no. 1, 2021, pp. 17936. [bibtex] [url] [doi]
[35]K. M. Detjen, R. Otto, Y. Giesecke, L. Geisler, P. Riemer, H. Jann, C. Grötzinger, C. Sers, A. Pascher, T. Lüdde, U. Leser, B. Wiedenmann, M. Sigal, F. Tacke, C. Roderburg, L. Hammerich,
"Elevated Flt3L Predicts Long-Term Survival in Patients with High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms", Cancers, vol. 13, no. 17, 2021, pp. 4463. [bibtex] [url] [doi]
[34]A. Echle, N. T. Rindtorff, T. J. Brinker, T. Lüdde, A. T. Pearson, J. N. Kather,
"Deep learning in cancer pathology: a new generation of clinical biomarkers", British journal of cancer, vol. 124, no. 4, 2021, pp. 686–696. [bibtex] [url] [doi]
[33]M. S. Jördens, L. Heinrichs, S. H. Loosen, L. Wittig, V. Keitel, D. Schöler, M. Schulze-Hagen, C. Loberg, G. Antoch, W. T. Knoefel, T. Lüdde, G. Fluegen, C. Roderburg,
"Sarcopenia Predicts Cancer Mortality in Male but Not in Female Patients Undergoing Surgery for Cholangiocellular Carcinoma", Cancers / Molecular Diversity Preservation International (MDPI), vol. 13, no. 21, 2021, pp. 5359. [bibtex] [url] [doi]
[32]K. V. K. Koelfat, K. M. C. van Mierlo, T. M. Lodewick, J. G. Bloemen, G. van der Kroft, I. Amygdalos, U. P. Neumann, C. H. C. Dejong, P. L. M. Jansen, S. W. M. Olde Damink, F. G. Schaap,
"Bile Salt and FGF19 Signaling in the Early Phase of Human Liver Regeneration", Hepatology communications, vol. 5, no. 8, 2021, pp. 1400–1411. [bibtex] [url] [doi]
[31]S. H. Loosen, C. Roderburg, P. H. Alizai, A. A. Roeth, S. M. Schmitz, M. Vucur, M. Luedde, D. Schöler, P. Paffenholz, F. Tacke, C. Trautwein, T. Lüdde, U. P. Neumann, T. F. Ulmer,
"Comparative Analysis of Circulating Biomarkers for Patients Undergoing Resection of Colorectal Liver Metastases", Diagnostics, vol. 11, no. 11, 2021, pp. 1999. [bibtex] [url] [doi]
[30]S. H. Loosen, V. van den Bosch, J. Gorgulho, M. Schulze-Hagen, J. Kandler, M. S. Jördens, F. Tacke, C. Loberg, G. Antoch, T. Brümmendorf, U. P. Neumann, C. K. Kuhl, T. Lüdde, C. Roderburg,
"Progressive Sarcopenia Correlates with Poor Response and Outcome to Immune Checkpoint Inhibitor Therapy", Journal of Clinical Medicine, vol. 10, no. 7, 2021, pp. 1361. [bibtex] [url] [doi]
[29]S. H. Loosen, H. H. Bock, M. Hellmich, W. T. Knoefel, C. Trautwein, V. Keitel, J. G. Bode, U. P. Neumann, T. Lüdde,
"Hospital Mortality and Current Trends in Liver Transplantation in Germany", Deutsches Ärzteblatt international, vol. 118, no. 29/30, 2021, pp. 497–502. [bibtex] [url] [doi]
[28]S. H. Loosen, J. Gorgulho, M. S. Jördens, M. Schulze-Hagen, F. Beier, M. Vucur, A. T. Schneider, C. Koppe, A. Mertens, J. N. Kather, F. Tacke, V. Keitel, T. H. Brümmendorf, C. Roderburg, T. Lüdde,
"Serum Levels of Soluble Urokinase Plasminogen Activator Receptor Predict Tumor Response and Outcome to Immune Checkpoint Inhibitor Therapy", Frontiers in oncology, vol. 11, 2021, pp. 646883. [bibtex] [url] [doi]
[27]S. H. Loosen, P. Paffenholz, T. Lüdde, K. Kostev, C. Roderburg,
"Diverticular disease is associated with an increased incidence rate of depression and anxiety disorders", International journal of colorectal disease, vol. 36, no. 11, 2021, pp. 2437–2443. [bibtex] [url] [doi]
[26]K. Müller, H. Honcharova-Biletska, C. Koppe, M. Egger, L. K. Chan, A. T. Schneider, L. Küsgens, F. Böhm, Y. Boege, M. E. Healy, J. Schmitt, S. Comtesse, M. Castoldi, C. Preisinger, M. Szydlowska, E. Focaccia, N. Gaisa, S. H. Loosen, S. Jörs, F. Tacke, C. Roderburg, V. Keitel, J. G. Bode, P. Boor, R. J. Davis, T. Longerich, F. Geisler, M. Heikenwalder, A. Weber, M. Vucur, T. Lüdde,
"JNK signaling prevents biliary cyst formation through a CASPASE-8-dependent function of RIPK1 during aging", Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 12, 2021, pp. e2007194118. [bibtex] [url] [doi]
[25]H. S. Muti, L. R. Heij, G. Keller, M. Kohlruss, R. Langer, B. Dislich, J. Cheong, Y. Kim, H. Kim, M. Kook, D. Cunningham, W. H. Allum, R. E. Langley, M. G. Nankivell, P. Quirke, J. D. Hayden, N. P. West, A. J. Irvine, T. Yoshikawa, T. Oshima, R. Huss, B. Grosser, F. Roviello, A. d'Ignazio, A. Quaas, H. Alakus, X. Tan, A. T. Pearson, T. Lüdde, M. P. Ebert, D. Jäger, C. Trautwein, N. T. Gaisa, H. I. Grabsch, J. N. Kather,
"Development and validation of deep learning classifiers to detect Epstein-Barr virus and microsatellite instability status in gastric cancer", The lancet / Digital health, vol. 3, no. 10, 2021, pp. e654–e664. [bibtex] [url] [doi]
[24]C. Roderburg, S. H. Loosen, J. Bednarsch, P. H. Alizai, A. A. Roeth, S. M. Schmitz, M. Vucur, M. Luedde, P. Paffenholz, F. Tacke, C. Trautwein, T. F. Ulmer, U. P. Neumann, T. Lüdde,
"Levels of Circulating PD-L1 Are Decreased in Patients with Resectable Cholangiocarcinoma", International journal of molecular sciences, vol. 22, no. 12, 2021, pp. 6569. [bibtex] [url] [doi]
[23]C. Roderburg, S. H. Loosen, A. Kunstein, R. Mohr, M. S. Jördens, M. Luedde, K. Kostev, T. Lüdde,
"Cancer Patients Have an Increased Incidence of Dementia: A Retrospective Cohort Study of 185,736 Outpatients in Germany", Cancers, vol. 13, no. 9, 2021, pp. 2027. [bibtex] [url] [doi]
[22]B. Rolles, J. Gorgulho, M. Tometten, C. Roderburg, M. Vieri, A. Abels, M. Vucur, F. Heymann, F. Tacke, T. H. Brümmendorf, T. Lüdde, F. Beier, S. H. Loosen,
"Telomere Shortening in Peripheral Leukocytes Is Associated With Poor Survival in Cancer Patients Treated With Immune Checkpoint Inhibitor Therapy", Frontiers in oncology, vol. 11, 2021, pp. 729207. [bibtex] [url] [doi]
[21]M. F. Schulze-Hagen, C. Roderburg, T. H. Wirtz, M. S. Jördens, L. Bündgens, S. Abu Jhaisha, P. Hohlstein, J. F. Brozat, P. Bruners, C. Loberg, C. K. Kuhl, C. Trautwein, F. Tacke, T. Lüdde, S. H. Loosen, A. Koch,
"Decreased Bone Mineral Density Is a Predictor of Poor Survival in Critically Ill Patients", Journal of Clinical Medicine, vol. 10, no. 16, 2021, pp. 3741. [bibtex] [url] [doi]
2022
[20]J. Bednarsch, Z. Czigany, L. R. Heij, I. Amygdalos, D. Heise, P. Bruners, T. F. Ulmer, U. P. Neumann, S. A. Lang,
"The role of re-resection in recurrent hepatocellular carcinoma", Langenbeck's archives of surgery, 2022, pp. 11 Seiten. [bibtex] [url] [doi]
[19]A. Ghallab, R. Hassan, U. Hofmann, A. Friebel, Z. Hobloss, L. Brackhagen, B. Begher-Tibbe, M. Myllys, J. Reinders, N. Overbeck, S. Sezgin, S. Zühlke, A. Seddek, W. Murad, T. Brecklinghaus, F. Kappenberg, J. Rahnenführer, D. González, C. Goldring, I. M. Copple, R. Marchan, T. Longerich, M. Vucur, T. Lüdde, S. Urban, A. Canbay, T. Schreiter, M. Trauner, J. Y. Akakpo, M. Olyaee, S. C. Curry, J. Sowa, H. Jaeschke, S. Hoehme, J. G. Hengstler,
"Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity", Journal of hepatology, vol. 77, no. 1, 2022, pp. 71–83. [bibtex] [url] [doi]
[18]S. Krieg, T. Essing, A. Krieg, C. Roderburg, T. Lüdde, S. H. Loosen,
"Recent Trends and In-Hospital Mortality of Transarterial Chemoembolization (TACE) in Germany: A Systematic Analysis of Hospital Discharge Data between 2010 and 2019", Cancers, vol. 14, no. 9, 2022, pp. 2088. [bibtex] [url] [doi]
[17]S. Krieg, C. Roderburg, A. Krieg, T. Lüdde, S. H. Loosen, K. Kostev,
"The association between body height and cancer: a retrospective analysis of 784,192 outpatients in Germany", Journal of cancer research and clinical oncology, 2022. [bibtex] [url] [doi]
[16]I. Labiano, A. Agirre-Lizaso, P. Olaizola, A. Echebarria, M. Huici-Izagirre, I. Olaizola, A. Esparza-Baquer, O. Sharif, E. Hijona, P. Milkiewicz, M. Milkiewicz, F. González-Romero, P. Aspichueta, M. J. Monte, J. J. G. Marin, M. Vucur, T. Lüdde, M. Marzioni, D. A. Mann, L. Bujanda, P. M. Rodrigues, J. M. Banales, M. J. Perugorria,
"TREM-2 plays a protective role in cholestasis by acting as a negative regulator of inflammation", Journal of hepatology, vol. 77, no. 4, 2022, pp. 991–1004. [bibtex] [url] [doi]
[15]D. Liu, L. R. Heij, Z. Czigany, E. Dahl, S. A. Lang, T. F. Ulmer, T. Lüdde, U. P. Neumann, J. Bednarsch,
"The role of tumor-infiltrating lymphocytes in cholangiocarcinoma", Journal of experimental & clinical cancer research, vol. 41, no. 1, 2022, pp. 127. [bibtex] [url] [doi]
[14]D. Liu, L. Heij, Z. Czigany, E. Dahl, M. Den Dulk, S. Lang, T. F. Ulmer, U. P. Neumann, J. Bednarsch,
"The prognostic value of neutrophil-to-lymphocyte ratio in cholangiocarcinoma", Scientific reports, vol. 12, 2022, pp. 12691. [bibtex] [url] [doi]
[13]S. H. Loosen, J. F. Halpaap, S. Labuhn, J. Bednarsch, P. H. Alizai, A. A. Roeth, S. A. Lang, M. Vucur, J. N. Kather, W. T. Knoefel, T. F. Ulmer, U. P. Neumann, C. Roderburg, T. Lüdde,
"Golgi Protein 73 (GP73) Serum Levels Predict Outcome after Resection of Biliary Tract Cancer", Cancers, vol. 14, no. 18, 2022, pp. 4428. [bibtex] [url] [doi]
[12]S. H. Loosen, K. Kostev, M. S. Jördens, T. Lüdde, C. Roderburg,
"Overlap between irritable bowel syndrome and common gastrointestinal diagnoses: a retrospective cohort study of 29,553 outpatients in Germany", BMC gastroenterology, vol. 22, no. 1, 2022, pp. 48. [bibtex] [url] [doi]
[11]S. H. Loosen, D. Schöler, M. Luedde, J. Eschrich, T. Lüdde, K. Kostev, C. Roderburg,
"Differential role of chronic liver diseases on the incidence of cancer: a longitudinal analysis among 248,224 outpatients in Germany", Journal of cancer research and clinical oncology, 2022, pp. 7 Seiten. [bibtex] [url] [doi]
[10]S. H. Loosen, C. Roderburg, M. S. Jördens, G. Fluegen, T. Lüdde, K. Kostev,
"Overweight and Obesity Determine the Risk for Gastrointestinal Cancer in a Sex-Dependent Manner: A Retrospective Cohort Study of 287,357 Outpatients in Germany", Cancers, vol. 14, no. 4, 2022, pp. 931. [bibtex] [url] [doi]
[9]S. H. Loosen, T. Essing, M. Jördens, A. Koch, F. Tacke, W. T. Knoefel, J. Bode, C. Roderburg, T. Lüdde,
"Current epidemiological trends and in-hospital mortality of acute pancreatitis in Germany: a systematic analysis of standardized hospital discharge data between 2008 and 2017", Zeitschrift für Gastroenterologie, vol. 60, no. 03, 2022, pp. 310–319. [bibtex] [url] [doi]
[8]S. H. Loosen, B. O. Jensen, C. Tanislav, T. Lüdde, C. Roderburg, K. Kostev,
"Obesity and lipid metabolism disorders determine the risk for development of long COVID syndrome: a cross-sectional study from 50,402 COVID-19 patients", Infection, vol. 50, no. 5, 2022, pp. 1165–1170. [bibtex] [url] [doi]
[7]S. H. Loosen, T. F. Ulmer, S. Labuhn, J. Bednarsch, S. Lang, P. H. Alizai, A. T. Schneider, M. Vucur, U. P. Neumann, T. Lüdde, C. Roderburg,
"Serum Levels of CXCL13 Are an Independent Predictor of Survival Following Resection of Biliary Tract Cancer", Cancers, vol. 14, no. 17, 2022, pp. 4073. [bibtex] [url] [doi]
[6]C. Roderburg, T. Essing, L. Kehmann, S. Krieg, S. Labuhn, J. Kandler, T. Lüdde, S. H. Loosen,
"Current Trends in Inpatient Care and In-Hospital Mortality of Cholangiocarcinoma in Germany: A Systematic Analysis between 2010 and 2019", Cancers, vol. 14, no. 16, 2022, pp. 4038. [bibtex] [url] [doi]
[5]D. Schöler, K. Kostev, M. Demir, M. Luedde, M. Konrad, T. Lüdde, C. Roderburg, S. H. Loosen,
"An Elevated FIB-4 Score Is Associated with an Increased Incidence of Depression among Outpatients in Germany", Journal of Clinical Medicine, vol. 11, no. 8, 2022, pp. 2214. [bibtex] [url] [doi]
[4]G. Wang, L. R. Heij, D. Liu, E. Dahl, S. A. Lang, T. F. Ulmer, T. Lüdde, U. P. Neumann, J. Bednarsch,
"The Role of Single-Nucleotide Polymorphisms in Cholangiocarcinoma: A Systematic Review", Cancers, vol. 14, no. 23, 2022, pp. 5969. [bibtex] [url] [doi]
2023
[3]X. Chang, R. Korenblik, B. Olij, R. R. M. M. Knapen, C. van der Leij, D. Heise, M. den Dulk, U. P. Neumann, F. G. Schaap, R. M. van Dam, S. W. M. Olde Damink,
"Influence of cholestasis on portal vein embolization-induced hypertrophy of the future liver remnant", Langenbeck's archives of surgery, vol. 408, no. 1, 2023, pp. 54. [bibtex] [url] [doi]
[2]T. Essing, H. Bock, B. Wieland, G. Fluegen, J. Bednarsch, J. G. Bode, U. P. Neumann, C. Roderburg, S. H. Loosen, T. Lüdde,
"Clinical determinants of hospital mortality in liver failure: a comprehensive analysis of 62,717 patients", Zeitschrift für Gastroenterologie, 2023, pp. a-2016–9061. [bibtex] [url] [doi]
[1]C. Roderburg, S. H. Loosen, M. S. Joerdens, M. Demir, T. Lüdde, K. Kostev,
"Antibiotic therapy is associated with an increased incidence of cancer", Journal of cancer research and clinical oncology, vol. 149, no. 3, 2023, pp. 1285–1293. [bibtex] [url] [doi]