|
| [43] | S. Loosen, M. F. Schulze-Hagen, P. Bruners, F. Tacke, C. Trautwein, C. K. Kuhl, T. Lüdde, C. Roderburg,
"Sarcopenia Is a Negative Prognostic Factor in Patients Undergoing Transarterial Chemoembolization (TACE) for Hepatic Malignancies", Cancers, vol. 11, no. 10, 2019, pp. 1503.
|
|
| [42] | M. Bartneck, C. Koppe, V. Fech, K. T. Warzecha, M. Kohlhepp, S. Huss, R. Weiskirchen, C. Trautwein, T. Lüdde, F. Tacke,
"Roles of CCR2 and CCR5 for Hepatic Macrophage Polarization in Mice With Liver Parenchymal Cell-Specific NEMO Deletion", Cellular and Molecular Gastroenterology and Hepatology, vol. 11, no. 2, 2020, pp. 327–347.
|
| [41] | L. Buendgens, E. Yagmur, A. Ginsberg, R. Weiskirchen, T. Wirtz, S. A. Jhaisha, A. Eisert, T. Lüdde, C. Trautwein, F. Tacke, A. Koch,
"Midregional Proadrenomedullin (MRproADM) Serum Levels in Critically Ill Patients Are Associated with Short-Term and Overall Mortality during a Two-Year Follow-Up", Mediators of inflammation, vol. 2020, 2020, pp. 7184803.
|
| [40] | H. K. Drescher, A. Schippers, S. Rosenhain, F. Gremse, L. Bongiovanni, A. de Bruin, S. Eswaran, S. U. Gallage, D. Pfister, M. Szydlowska, M. Heikenwalder, S. Weiskirchen, N. Wagner, C. Trautwein, R. Weiskirchen, D. C. Kroy,
"L-Selectin/CD62L is a Key Driver of Non-Alcoholic Steatohepatitis in Mice and Men", Cells, vol. 9, no. 5, 2020, pp. 1106.
|
| [39] | A. Echle, H. I. Grabsch, P. Quirke, P. A. van den Brandt, N. P. West, G. G. A. Hutchins, L. R. Heij, X. Tan, S. D. Richman, J. Krause, E. Alwers, J. Jenniskens, K. Offermans, R. Gray, H. Brenner, J. Chang-Claude, C. Trautwein, A. T. Pearson, P. Boor, T. Lüdde, N. T. Gaisa, M. Hoffmeister, J. N. Kather,
"Clinical-Grade Detection of Microsatellite Instability in Colorectal Tumors by Deep Learning", Gastroenterology, vol. 159, no. 4, 2020, pp. 1406–1416.e11.
|
| [38] | J. N. Kather, L. R. Heij, H. I. Grabsch, C. Loeffler, A. Echle, H. S. Muti, J. Krause, J. M. Niehues, K. A. J. Sommer, P. Bankhead, L. F. S. Kooreman, J. J. Schulte, N. A. Cipriani, R. D. Buelow, P. Boor, N. Ortiz-Brüchle, A. M. Hanby, V. Speirs, S. Kochanny, A. Patnaik, A. Srisuwananukorn, H. Brenner, M. Hoffmeister, P. A. van den Brandt, D. Jäger, C. Trautwein, A. T. Pearson, T. Lüdde,
"Pan-cancer image-based detection of clinically actionable genetic alterations", Nature cancer, vol. 1, no. 8, 2020, pp. 789–799.
|
| [37] | A. Liepelt, P. Hohlstein, H. Gussen, J. Xue, A. C. Aschenbrenner, T. Ulas, L. Bündgens, K. T. Warzecha, M. Bartneck, T. Lüdde, C. Trautwein, J. L. Schultze, A. Koch, F. Tacke,
"Differential Gene Expression in Circulating CD14+ Monocytes Indicates the Prognosis of Critically Ill Patients with Sepsis", Journal of Clinical Medicine, vol. 9, no. 1, 2020, pp. 127.
|
| [36] | T. Puengel, S. De Vos, J. Hundertmark, M. Kohlhepp, N. Guldiken, P. Pujuguet, M. Auberval, F. Marsais, K. F. Shoji, L. Saniere, C. Trautwein, T. Lüdde, P. Strnad, R. Brys, P. Clément-Lacroix, F. Tacke,
"The Medium-Chain Fatty Acid Receptor GPR84 Mediates Myeloid Cell Infiltration Promoting Steatohepatitis and Fibrosis", Journal of Clinical Medicine, vol. 9, no. 4, 2020, pp. 1140.
|
| [35] | A. Queck, H. Bode, F. E. Uschner, M. J. Brol, C. Graf, M. Schulz, C. Jansen, M. Praktiknjo, R. Schierwagen, S. Klein, C. Trautwein, H. E. Wasmuth, M. Berres, J. Trebicka, J. Lehmann,
"Systemic MCP-1 Levels Derive Mainly From Injured Liver and Are Associated With Complications in Cirrhosis", Frontiers in immunology, vol. 11, 2020, pp. 354.
|
| [34] | A. Riba, K. Hassani, A. Walker, N. van Best, D. von Zeschwitz, T. Anslinger, N. Sillner, S. Rosenhain, D. Eibach, O. Maiga-Ascofaré, U. Rolle-Kampczyk, M. Basic, A. Binz, S. Mocek, B. Sodeik, R. Bauerfeind, A. Mohs, C. Trautwein, F. Kießling, J. May, M. Klingenspor, F. Gremse, P. Schmitt-Kopplin, A. Bleich, N. Torow, M. von Bergen, M. W. Hornef,
"Disturbed gut microbiota and bile homeostasis in Giardia-infected mice contributes to metabolic dysregulation and growth impairment", Science translational medicine, vol. 12, no. 565, 2020, pp. eaay7019.
|
| [33] | T. Wirtz, S. H. Loosen, L. Buendgens, B. Kurt, S. Abu Jhaisha, P. Hohlstein, J. F. Brozat, R. Weiskirchen, T. Lüdde, F. Tacke, C. Trautwein, C. Roderburg, A. Koch,
"Low Myostatin Serum Levels Are Associated with Poor Outcome in Critically Ill Patients", Diagnostics, vol. 10, no. 8, 2020.
|
| [32] | T. Wirtz, L. Buendgens, R. Weiskirchen, S. H. Loosen, N. Haehnsen, T. Puengel, S. Abu Jhaisha, J. F. Brozat, P. Hohlstein, G. Koek, A. Eisert, R. Mohr, C. Roderburg, T. Lüdde, C. Trautwein, F. Tacke, A. Koch,
"Association of Serum Calprotectin Concentrations with Mortality in Critically Ill and Septic Patients", Diagnostics, vol. 10, no. 11, 2020.
|
|
| [31] | V. Baier, O. Clayton, R. Nudischer, H. Cordes, A. R. P. Schneider, C. W. J. Thiel, T. Wittenberger, W. Moritz, L. M. Blank, U. P. Neumann, C. Trautwein, J. Kelm, Y. Schrooders, F. Caiment, H. Gmuender, A. Roth, J. V. Castell, J. Kleinjans, L. O. Küpfer,
"A Model-Based Workflow to Benchmark the Clinical Cholestasis Risk of Drugs", Clinical pharmacology & therapeutics, vol. 110, no. 5, 2021, pp. 1293–1301.
|
| [30] | R. Benedé-Ubieto, O. Estévez-Vázquez, F. Guo, C. Chen, Y. Singh, H. I. Nakaya, M. Gómez Del Moral, A. Lamas-Paz, L. Morán, N. López-Alcántara, J. Reissing, T. Bruns, M. A. Avila, E. Santamaría, M. S. Mazariegos, M. M. Woitok, U. Haas, K. Zheng, I. Juárez, J. M. Martín-Villa, I. Asensio, J. Vaquero, M. I. Peligros, J. Argemi, R. Bataller, J. Ampuero, M. Romero Gómez, C. Trautwein, C. Liedtke, R. Bañares, F. J. Cubero, Y. A. Nevzorova,
"An Experimental DUAL Model of Advanced Liver Damage", Hepatology communications, vol. 5, no. 6, 2021, pp. 1051–1068.
|
| [29] | O. Estévez-Vázquez, R. Benedé-Ubieto, F. Guo, B. Gómez-Santos, P. Aspichueta, J. Reißing, T. Bruns, C. Sanz-García, S. Sydor, L. P. Bechmann, E. Maranillo, J. R. Sañudo, M. T. Vázquez, A. Lamas-Paz, L. Morán, M. S. Mazariegos, A. Ciudin, J. M. Pericàs, M. I. Peligros, J. Vaquero, E. Martínez-Naves, C. Liedtke, J. R. Regueiro, C. Trautwein, R. Bañares, F. J. Cubero, Y. A. Nevzorova,
"Fat", Biomedicines, vol. 9, no. 10, 2021, pp. 1289.
|
| [28] | S. Eswaran, A. Babbar, H. K. Drescher, T. C. A. Hitch, T. Clavel, M. Muschaweck, T. Ritz, D. C. Kroy, C. Trautwein, N. Wagner, A. Schippers,
"Upregulation of anti-oxidative stress response improves metabolic changes in l-selectin-deficient mice but does not prevent NAFLD progression or fecal microbiota shifts", International journal of molecular sciences, vol. 22, no. 14, 2021, pp. 7314.
|
| [27] | N. Guldiken, J. Argemi, B. Gurbuz, S. R. Atkinson, M. Oliverius, P. Fila, K. Hamesch, T. Bruns, J. Cabezas, J. J. Lozano, J. Mann, S. Cao, P. Mathurin, V. H. Shah, C. Trautwein, M. R. Thursz, R. Bataller, P. Strnad,
"Serum transferrin as a biomarker of hepatocyte nuclear factor 4 alpha activity and hepatocyte function in liver diseases", BMC medicine, vol. 19, 2021, pp. 39.
|
| [26] | K. Große, D. Ohm, S. Würstle, J. F. Brozat, R. M. Schmid, C. Trautwein, A. Stallmach, T. Bruns, P. A. Reuken,
"Clinical characteristics and outcome of patients with enterococcal liver abscess", Scientific reports, vol. 11, no. 1, 2021, pp. 22265.
|
| [25] | D. Heinrichs, E. F. Brandt, P. Fischer, J. Köhncke, T. Wirtz, N. Guldiken, S. Djudjaj, P. Boor, D. C. Kroy, R. Weiskirchen, R. Bucala, H. E. Wasmuth, P. Strnad, C. Trautwein, J. Bernhagen, M. Berres,
"Unexpected Pro-Fibrotic Effect of MIF in Non-Alcoholic Steatohepatitis Is Linked to a Shift in NKT Cell Populations", Cells, vol. 10, no. 2, 2021, pp. 252.
|
| [24] | B. Kurt, L. Bündgens, T. Wirtz, S. H. Loosen, M. Schulze-Hagen, D. Truhn, J. F. Brozat, S. Abu Jhaisha, P. Hohlstein, G. Koek, R. Weiskirchen, C. Trautwein, F. Tacke, K. Hamesch, A. Koch,
"Serum Perilipin 2 (PLIN2) Predicts Multiple Organ Dysfunction in Critically Ill Patients", Biomedicines, vol. 9, no. 9, 2021, pp. 1210.
|
| [23] | S. H. Loosen, C. Roderburg, P. H. Alizai, A. A. Roeth, S. M. Schmitz, M. Vucur, M. Luedde, D. Schöler, P. Paffenholz, F. Tacke, C. Trautwein, T. Lüdde, U. P. Neumann, T. F. Ulmer,
"Comparative Analysis of Circulating Biomarkers for Patients Undergoing Resection of Colorectal Liver Metastases", Diagnostics, vol. 11, no. 11, 2021, pp. 1999.
|
| [22] | S. H. Loosen, H. H. Bock, M. Hellmich, W. T. Knoefel, C. Trautwein, V. Keitel, J. G. Bode, U. P. Neumann, T. Lüdde,
"Hospital Mortality and Current Trends in Liver Transplantation in Germany", Deutsches Ärzteblatt international, vol. 118, no. 29/30, 2021, pp. 497–502.
|
| [21] | H. S. Muti, L. R. Heij, G. Keller, M. Kohlruss, R. Langer, B. Dislich, J. Cheong, Y. Kim, H. Kim, M. Kook, D. Cunningham, W. H. Allum, R. E. Langley, M. G. Nankivell, P. Quirke, J. D. Hayden, N. P. West, A. J. Irvine, T. Yoshikawa, T. Oshima, R. Huss, B. Grosser, F. Roviello, A. d'Ignazio, A. Quaas, H. Alakus, X. Tan, A. T. Pearson, T. Lüdde, M. P. Ebert, D. Jäger, C. Trautwein, N. T. Gaisa, H. I. Grabsch, J. N. Kather,
"Development and validation of deep learning classifiers to detect Epstein-Barr virus and microsatellite instability status in gastric cancer", The lancet / Digital health, vol. 3, no. 10, 2021, pp. e654–e664.
|
| [20] | C. Roderburg, S. H. Loosen, J. Bednarsch, P. H. Alizai, A. A. Roeth, S. M. Schmitz, M. Vucur, M. Luedde, P. Paffenholz, F. Tacke, C. Trautwein, T. F. Ulmer, U. P. Neumann, T. Lüdde,
"Levels of Circulating PD-L1 Are Decreased in Patients with Resectable Cholangiocarcinoma", International journal of molecular sciences, vol. 22, no. 12, 2021, pp. 6569.
|
| [19] | K. M. Schneider, C. Elfers, A. Ghallab, C. V. Schneider, E. J. C. Galvez, A. Mohs, W. Gui, L. S. Candels, T. Wirtz, S. Zuehlke, M. Spiteller, M. Myllys, A. Roulet, A. Ouzerdine, B. Lelouvier, K. Kilic, L. Liao, A. Nier, E. Latz, I. Bergheim, C. A. Thaiss, J. G. Hengstler, T. Strowig, C. Trautwein,
"Intestinal Dysbiosis Amplifies Acetaminophen-Induced Acute Liver Injury", Cellular and Molecular Gastroenterology and Hepatology, vol. 11, no. 4, 2021, pp. 909–933.
|
| [18] | M. F. Schulze-Hagen, C. Roderburg, T. H. Wirtz, M. S. Jördens, L. Bündgens, S. Abu Jhaisha, P. Hohlstein, J. F. Brozat, P. Bruners, C. Loberg, C. K. Kuhl, C. Trautwein, F. Tacke, T. Lüdde, S. H. Loosen, A. Koch,
"Decreased Bone Mineral Density Is a Predictor of Poor Survival in Critically Ill Patients", Journal of Clinical Medicine, vol. 10, no. 16, 2021, pp. 3741.
|
| [17] | T. Streidl, I. Karkossa, R. R. Segura Muñoz, C. Eberl, A. Zaufel, J. Plagge, R. Schmaltz, K. Schubert, M. Basic, K. M. Schneider, M. Afify, C. Trautwein, R. H. Tolba, B. Stecher, H. L. Doden, J. M. Ridlon, J. Ecker, T. Moustafa, M. von Bergen, A. E. Ramer-Tait, T. Clavel,
"The gut bacterium Extibacter muris produces secondary bile acids and influences liver physiology in gnotobiotic mice", Gut microbes, vol. 13, no. 1, 2021, pp. 1–21.
|
| [16] | J. Voss, C. V. Schneider, M. Kleinjans, T. Bruns, C. Trautwein, P. Strnad,
"Hepatobiliary phenotype of individuals with chronic intestinal disorders", Scientific reports, vol. 11, 2021, pp. 19954.
|
| [15] | T. Wirtz, P. A. Reuken, C. Jansen, P. Fischer, I. Bergmann, C. Backhaus, C. Emontzpohl, J. Reißing, E. F. Brandt, M. T. Koenen, K. M. Schneider, R. Schierwagen, M. J. Brol, J. Chang, H. W. Zimmermann, N. Köse-Vogel, T. Eggermann, I. Kurth, C. Stoppe, R. Bucala, J. Bernhagen, M. Praktiknjo, A. Stallmach, C. Trautwein, J. Trebicka, T. Bruns, M. Berres,
"Balance between macrophage migration inhibitory factor and sCD74 predicts outcome in patients with acute decompensation of cirrhosis", JHEP reports, vol. 3, no. 2, 2021, pp. 100221.
|
| [14] | T. Wirtz, A. Saal, I. Bergmann, P. Fischer, D. Heinrichs, E. F. Brandt, M. T. Koenen, S. Djudjaj, K. M. Schneider, P. Boor, R. Bucala, R. Weiskirchen, J. Bernhagen, C. Trautwein, M. Berres,
"Macrophage migration inhibitory factor exerts pro‐proliferative and anti‐apoptotic effects via CD74 in murine hepatocellular carcinoma", British journal of pharmacology, vol. 178, no. 22, 2021, pp. 4452–4467.
|
|
| [13] | J. F. Brozat, E. F. Brandt, M. Stark, P. Fischer, T. Wirtz, A. Flaßhove, A. N. Rodenhausen, T. Vajen, A. C. A. Heinzmann, S. M. Schmitz, S. Abu Jhaisha, A. A. J. Röth, R. R. Koenen, H. Sahin, C. Trautwein, M. Berres,
"JAM‐A is a multifaceted regulator in hepatic fibrogenesis, supporting LSEC integrity and stellate cell quiescence", Liver international, vol. 42, no. 5, 2022, pp. 1185–1203.
|
| [12] | J. F. Brozat, F. Hanses, M. Haelberger, M. Stecher, M. Dreher, L. Tometten, M. M. Ruethrich, J. J. Vehreschild, C. Trautwein, S. Borgmann, M. J. G. T. Vehreschild, C. E. M. Jakob, A. Stallmach, K. Wille, K. Hellwig, N. Isberner, P. A. Reuken, F. Geisler, J. Nattermann, T. Bruns, L. study group,
"COVID‐19 mortality in cirrhosis is determined by cirrhosis‐associated comorbidities and extrahepatic organ failure: Results from the multinational LEOSS registry", United european gastroenterology journal, vol. 10, no. 4, 2022, pp. 409–424.
|
| [11] | L. S. Candels, S. Becker and C. Trautwein,
"PLA2G7: a new player in shaping energy metabolism and lifespan", Signal transduction and targeted therapy, vol. 7, no. 1, 2022, pp. 195.
|
| [10] | L. Colyn, G. Alvarez-Sola, M. U. Latasa, I. Uriarte, J. M. Herranz, M. Arechederra, G. Vlachogiannis, C. Rae, A. Pineda-Lucena, A. Casadei-Gardini, F. Pedica, L. Aldrighetti, A. López-López, A. López-Gonzálvez, C. Barbas, S. Ciordia, S. M. Van Liempd, J. M. Falcón-Pérez, J. Urman, B. Sangro, S. Vicent, M. J. Iraburu, F. Prosper, L. J. Nelson, J. M. Banales, M. L. Martinez-Chantar, J. J. G. Marin, C. Braconi, C. Trautwein, F. J. Corrales, F. J. Cubero, C. Berasain, M. G. Fernandez-Barrena, M. A. Avila,
"New molecular mechanisms in cholangiocarcinoma: signals triggering interleukin-6 production in tumor cells and KRAS co-opted epigenetic mediators driving metabolic reprogramming", Journal of experimental & clinical cancer research, vol. 41, 2022, pp. 183.
|
| [9] | M. Fromme, C. V. Schneider, C. Schlapbach, S. Cazzaniga, C. Trautwein, D. J. Rader, L. Borradori, P. Strnad,
"Comorbidities in lichen planus by phenome‐wide association study in two biobank population cohorts", British journal of dermatology, vol. 187, no. 5, 2022, pp. 722–729.
|
| [8] | F. Guo, O. Estévez-Vázquez, R. Benedé-Ubieto, D. Maya-Miles, K. Zheng, R. Gallego-Durán, . Rojas, J. Ampuero, M. Romero-Gómez, K. Philip, I. U. Egbuniwe, C. Chen, J. Simon, T. C. Delgado, M. L. Martínez-Chantar, J. Sun, J. Reissing, T. Bruns, A. Lamas-Paz, M. G. D. Moral, M. M. Woitok, J. Vaquero, J. R. Regueiro, C. Liedtke, C. Trautwein, R. Bañares, F. J. Cubero, Y. A. Nevzorova,
"A Shortcut from Metabolic-Associated Fatty Liver Disease (MAFLD) to Hepatocellular Carcinoma (HCC): c-MYC a Promising Target for Preventative Strategies and Individualized Therapy", Cancers, vol. 14, no. 1, 2022, pp. 192.
|
| [7] | S. Haange, A. Till, P. Bergh, G. Fauler, M. Gigl, A. Löfgren-Sandblom, F. G. Schaap, T. Clavel, C. Trautwein, W. Fenske, K. Kleigrewe, H. Marschall, S. W. M. Olde Damink, T. Moustafa, M. von Bergen, U. Rolle-Kampczyk,
"Ring Trial on Quantitative Assessment of Bile Acids Reveals a Method- and Analyte-Specific Accuracy and Reproducibility", Metabolites, vol. 12, no. 7, 2022, pp. 583.
|
| [6] | T. Puengel, B. Weber, T. Wirtz, L. Buendgens, S. H. Loosen, L. Geisler, B. Özdirik, H. Karim, S. A. Jhaisha, J. F. Brozat, P. Hohlstein, A. Eisert, E. Yagmur, C. Trautwein, F. Tacke, A. Koch,
"Low Serum Levels of Soluble Receptor Activator of Nuclear Factor κ B Ligand (sRANKL) Are Associated with Metabolic Dysregulation and Predict Long-Term Mortality in Critically Ill Patients", Diagnostics, vol. 12, no. 1, 2022, pp. 62.
|
| [5] | P. A. Reuken, J. F. Brozat, S. Quickert, O. Ibidapo-obe, J. Reißing, A. Franz, S. Stengel, U. K. Teichgräber, M. Kiehntopf, C. Trautwein, A. Stallmach, A. Koch, T. Bruns,
"Soluble mannose receptor CD206 and von Willebrand factor are early biomarkers to identify patients at risk for severe or necrotizing acute pancreatitis", Journal of Intensive Care, vol. 10, no. 1, 2022, pp. 28.
|
| [4] | A. R. P. Schneider, C. V. Schneider, K. M. Schneider, V. Baier, S. Schaper, C. Diedrich, K. Coboeken, H. Mayer, W. Gu, J. Trebicka, L. M. Blank, R. Burghaus, J. Lippert, D. J. Rader, C. A. Thaiss, J. Schlender, C. Trautwein, L. Küpfer,
"Early prediction of decompensation (EPOD) score: Non-invasive determination of cirrhosis decompensation risk", Liver international, vol. 42, no. 3, 2022, pp. 640–650.
|
| [3] | P. Strnad, M. Mandorfer, G. Choudhury, W. Griffiths, C. Trautwein, R. Loomba, T. Schluep, T. Chang, M. Yi, B. D. Given, J. C. Hamilton, J. San Martin, J. H. Teckman,
"Fazirsiran for Liver Disease Associated with Alpha 1 -Antitrypsin Deficiency", The New England journal of medicine, vol. 387, no. 6, 2022, pp. 514–524.
|
|
| [2] | H. Su, M. Haque, S. Becker, K. Edlund, J. Duda, Q. Wang, J. Reißing, H. Marschall, L. S. Candels, M. Mohamed, W. Sjöland, L. Liao, S. A. Drexler, T. Strowig, J. Rahnenführer, J. G. Hengstler, M. Hatting, C. Trautwein,
"Long‐term hypercaloric diet exacerbates metabolic liver disease in PNPLA3 I148M animals", Liver international, 2023.
|
| [1] | S. Torres, C. Ortiz, N. Bachtler, W. Gu, L. D. Grünewald, N. Kraus, R. Schierwagen, C. Hieber, C. Meier, O. Tyc, M. Joseph Brol, F. E. Uschner, B. Nijmeijer, C. Welsch, M. Berres, C. Garcia-Ruiz, J. C. Fernandez-Checa, C. Trautwein, T. J. Vogl, S. Zeuzem, J. Trebicka, S. Klein,
"Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis", Hepatology, vol. 77, no. 4, 2023, pp. 1228–1240.
|