Gut, Liver and Friends Seminar with Prof. Dr. Klaus-Peter Janssen

Prof. Dr. Klaus-Peter Janssen und Prof. Thomas Clavel

Prof. Dr. Klaus-Peter Janssen from Munich (TUM, Klinikum Rechts der Isar) was our guest at ‘Gut, Liver and Friends’ on February 19th 2020.

Klaus-Peter Janssen´s laboratory has a major interest in studying tumorigenesis in the colon and the impact of the gut microbiota. He shared brand new data obtained from patients and mouse models on the impact of the microbiota on colorectal cancer and experimental liver resection

Publications:

Holtorf A, Conrad A, Holzmann B, Janssen KP. Cell-type specific MyD88 signaling is required for intestinal tumor initiation and progression to malignancy. Oncoimmunology. 2018;7(8):e1466770. Published 2018 Jun 11. doi:10.1080/2162402X.2018.1466770

Franke FC, Müller J, Abal M, et al. The Tumor Suppressor SASH1 Interacts With the Signal Adaptor CRKL to Inhibit Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer. Cell Mol Gastroenterol Hepatol. 2018;7(1):33–53. Published 2018 Sep 11. doi:10.1016/j.jcmgh.2018.08.007

Cremonesi E, Governa V, Garzon JFG, et al. Gut microbiota modulate T cell trafficking into human colorectal cancer. Gut. 2018;67(11):1984–1994. doi:10.1136/gutjnl-2016-313498