Oliver Pabst, Prof. Dr. rer. nat.

Oliver Pabst is speaker of this CRC and PI in projects B06 and Q04 since the start of funding in 2019.

Institute of Molecular Medicine,
RWTH Aachen University

Pauwelsstraße 30, 52074 Aachen

Involved projects

To B06

B06

Topology and function of secretory antibodies in gut-liver communication

To B06
To Q04

Q04

Central tasks of the CRC

To Q04

Ugur, M., A. Kaminski, and O. Pabst. 2018. Lymph node gammadelta and alphabeta CD8(+) T cells share migratory properties. Scientific reports 8:8986.

Sethi, M.K., F. Thol, M. Stadler, M. Heuser, A. Ganser, C. Koenecke*, and O. Pabst*. 2017. VH1 Family immunoglobulin repertoire sequencing after allogeneic hematopoietic stem cell transplantation. PloS one 12:e0168096. *equal contribution

Lindner, C., I. Thomsen, B. Wahl, M. Ugur, M.K. Sethi, M. Friedrichsen, A. Smoczek, S. Ott, U. Baumann, S. Suerbaum, S. Schreiber, A. Bleich, V. Gaboriau-Routhiau, N. Cerf-Bensussan, H. Hazanov, R. Mehr, P. Boysen, P. Rosenstiel, and O. Pabst. 2015. Diversification of memory B cells drives the continuous adaptation of secretory antibodies to gut microbiota. Nature immunology 16:880-888.

Ugur, M., O. Schulz, M.B. Menon, A. Krueger, and O. Pabst. 2014. Resident CD4+ T cells accumulate in lymphoid organs after prolonged antigen exposure. Nature communications 5:4821.

Schulz, O., M. Ugur, M. Friedrichsen, K. Radulovic, J.H. Niess, S. Jalkanen, A. Krueger, and O. Pabst. 2014. Hypertrophy of infected Peyer’s patches arises from global, interferon-receptor, and CD69-independent shutdown of lymphocyte egress. Mucosal immunology 7:892-904.

Lindner, C., B. Wahl, L. Fohse, S. Suerbaum, A.J. Macpherson, I. Prinz, and O. Pabst. 2012. Age, microbiota, and T cells shape diverse individual IgA repertoires in the intestine. The Journal of experimental medicine 209:365-377.

Hadis, U., B. Wahl, O. Schulz, M. Hardtke-Wolenski, A. Schippers, N. Wagner, W. Muller, T. Sparwasser, R. Forster, and O. Pabst. 2011. Intestinal tolerance requires gut homing and expansion of FoxP3+ regulatory T cells in the lamina propria. Immunity 34:237-246.

Schulz, O., E. Jaensson, E.K. Persson, X. Liu, T. Worbs, W.W. Agace*, and O. Pabst*. 2009. Intestinal CD103+, but not CX3CR1+, antigen sampling cells migrate in lymph and serve classical dendritic cell functions. The Journal of experimental medicine 206:3101-3114. *equal contribution

Hammerschmidt, S.I., M. Ahrendt, U. Bode, B. Wahl, E. Kremmer, R. Forster, and O. Pabst. 2008. Stromal mesenteric lymph node cells are essential for the generation of gut-homing T cells in vivo. The Journal of experimental medicine 205:2483-2490.

Worbs, T., U. Bode, S. Yan, M.W. Hoffmann, G. Hintzen, G. Bernhardt, R. Forster*, and O. Pabst*. 2006. Oral tolerance originates in the intestinal immune system and relies on antigen carriage by dendritic cells. The Journal of experimental medicine 203:519-527. *equal contribution