Salmonella infection – non-professional efferocytosis contributes to barrier integrity in the neonate
Publication in the Journal of Experimental Medicine
Salmonella infection: Non-professional efferocytosis contributes to barrier integrity in the neonate
The immune system and the intestinal barrier of neonates and adult organisms are fundamentally different. Therefore, infections with the enteropathogen Salmonella have a different course and outcome in the neonate than in the adult. Mathias W. Hornef (B01), from our consortium and his team have published exiting results on how non-professional efferocytosis of Salmonella-infected epithelial cells by neighboring epithelial cells contributes to neonatal antimicrobial host defense.