Main Topics of the Symposium
- Diseases of the Gut-Liver Axis
- Microbiome and Gut-Liver Diseases
- Modelling the Gut-Liver Axis and Metabolism
- Immune Circuits in the Gut-Liver Axis
- The Role of Bile Acids in the Gut-Liver Axis
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Thursday 6 Oct 2022
8:00 – 9:00 Registration and coffee
No workshops in this session.
9:15 – 11:30 Session 1: Diseases of the gut-liver axis
chair persons: Marie Berres and Mathias Hornef
‘Nonbacterial Kingdoms of the Gut Microbiota and Alcohol-Associated Liver Disease’
Bernd SchnablSuperC (RWTH Aachen University)
‘Primary sclerosing cholangitis: immune dysregulation in disease pathogenesis‘
Christoph SchrammSuperC (RWTH Aachen University)
‘Gut-liver-axis and decompensation of liver cirrhosis’
Jonel TrebickaSuperC (RWTH Aachen University)
‘Immunogenetic approaches to identify the culprit antigen in inflammatory bowel diseases’
Andre FrankeSuperC (RWTH Aachen University)
‘Lost in transl(oc)ation: Human peritoneal immunity in cirrhosis’
Tony BrunsSuperC (RWTH Aachen University)
‘Macrophage heterogeneity in liver diseases’
Frank TackeSuperC (RWTH Aachen University)
‘The liver-gut axis in NASH-HCC’
Mathias HeikenwälderSuperC (RWTH Aachen University)
11:30 – 12:00 Coffee Break
No workshops in this session.
13:00 – 13:40 Lunch break
No workshops in this session.
13:45 – 15:15 Guided city tour
No workshops in this session.
15:15 – 15:45 Coffee Break
No workshops in this session.
15:45 – 18:00 Session 2: Microbiome and gut-liver diseases
Chair persons: Angela Schippers and Oliver Pabst
‘Causality or association of gutmicrobiota and their metabolites in human NAFLD-NASH; potential for new diagnostic and therapeutic leads’
Max NieuwdorpSuperC (RWTH Aachen University)
‘Exploring the gut-liver axis in cancer cachexia’
Laure BindelsSuperC (RWTH Aachen University)
‘Modulation of the Gut-Liver Axis through Fecal Microbiota Transfer’
Maria VehreschildSuperC (RWTH Aachen University)
‘Short-chain fatty acids and advanced chronic liver disease’
Rubén FrancésSuperC (RWTH Aachen University)
‘The gut liver axis during early life’
Mathias HornefSuperC (RWTH Aachen University)
18:00 – 19:30 Poster session
Reception with finger food and drinks
20:00 – 23:00 Dinner
invited speakers and PIs of CRC1382
Followed by open bar at Hotel Motel one, Aachen
Friday 7 Oct 2022
8:00 – 9:00 Registration and coffee
No workshops in this session.
9:00 – 9:05 Welcome
No workshops in this session.
9:05 – 12:45 Session 3: Immune circuits in the gut-liver axis
Chair persons: Vuk Cerovic and Pavel Strnad
Coffee break in between
‘Dendritic cells as cellular targets of gut-liver communication in chronic liver disease and hepatocellular carcinogenesis’
Marie BerresSuperC (RWTH Aachen University)
‘Development and function of the innate immune system’
Andreas DiefenbachSuperC (RWTH Aachen University)
‘Growing, flowing and sugar-coating in intestinal IgA responses’
Emma SlackSuperC (RWTH Aachen University)
‘Role of bacterial membrane vesicles along the gut-liver axis: Implications for novel therapeutic targets’
Claudia GüntherSuperC (RWTH Aachen University)
‘The gut liver axis in early life and as a tool for studying B cell specificity’
Andrew MacphersonSuperC (RWTH Aachen University)
‘Topology and function of secretory antibodies in gut-liver communication’
Oliver PabstSuperC (RWTH Aachen University)
‘Unravelling the cell-cell interactions forming the foundation of the macrophage niche’
Martin GuillaumsSuperC (RWTH Aachen University)
12:45 – 13:30 Lunch break
No workshops in this session.
13:30 – 15:30 Session 4: Metabolism and modelling the gut-liver axis
Chair persons: Heidi Noels and Thomas Clavel
‘Control of bile acid metabolism within the gut-liver-axis’
Christian TrautweinSuperC (RWTH Aachen University)
‘Physiologically-based computational models of bile acid metabolism’
Lars KüpferSuperC (RWTH Aachen University)
‘Quantitative Lipidomics – methods to analyze the Gut-Liver Axis’
Gerhard LiebischSuperC (RWTH Aachen University)
15:00 – 15:30 Coffee Break
No workshops in this session.
15:30 – 17:30 Session 5: The role of bile acids in gut-liver crosstalk
Chair persons: Martin von Bergen and Steven Olde-Damink
‘Bile salt signaling and homeostasis in the regenerating liver’
Frank SchaapSuperC (RWTH Aachen University)
‘Functional imaging of bile acid transport in liver diseases’
Jan HengstlerSuperC (RWTH Aachen University)
‘Hepatoprotective roles of the Bile Acid Receptor TGR5’
Thierry TordjmannSuperC (RWTH Aachen University)
‘Synthetic communities of cultured gut bacteria enables the functional study of bile acid metabolism in health and disease’
Thomas ClavelSuperC (RWTH Aachen University)