By Anne Eisele|2025-01-09T10:22:39+01:0009.01.2025|
New CRC publication in Liver International: Alpha-1 Antitrypsin Inclusions Sequester GRP78 in a Bile Acid-Inducible Manner Alpha-1 antitrypsin deficiency (AATD) is a rare genetic disorder that results in the accumulation of misfolded AAT protein in liver cells, causing chronic liver injury. Principal investigators (PIs) Prof. Pavel Strnad and Dr. Nurdan Guldiken from [...]
By Anne Eisele|2025-01-09T09:39:43+01:0009.01.2025|
New CRC publication in PNAS: Salmonella infection accelerates postnatal maturation of the intestinal epithelium The postnatal establishment of metabolic, host–microbial, and immune homeostasis is the result of precisely timed and tightly regulated developmental and adaptive processes. Tissue damage during this “neonatal window of opportunity” may disrupt these processes explaining human epidemiological data associating [...]
By Anne Eisele|2024-12-09T10:58:40+01:0009.12.2024|
CRC1382 3rd Project Day in November 2024 On November 29, 2024, the CRC1382 consortium met for the 3rd and last Project Day in 2024. Four projects presented their progress and received feedback from other CRC members. Like last time, dedicated PhD students moderated the sessions. The extended coffee breaks provided plenty of [...]
By Anne Eisele|2024-11-18T12:39:23+01:0018.11.2024|
Prof. Dr. med. Carolin Schneider has been awarded the Friedmund Neumann Prize 2024 On November 12, 2024, our PI Prof. Dr. med. Carolin Schneider received the Friedmund Neumann Prize 2024 by the Schering Stiftung at a festive ceremony in Berlin. The prize was awarded for her outstanding contributions to the prevention [...]
By Anne Eisele|2024-11-13T12:12:14+01:0013.11.2024|
CRC1382 at the 20th RWTH Science Night Last Friday, November 8th 2024, the outreach team of CRC1382 had its first stand ("Bacteria, Bile and Beyound") at the 20th RWTH Science Night! This event has been attracting thousands of visitors every year since 2003, with a unique way [...]
By Anne Eisele|2024-08-26T11:22:18+02:0026.08.2024|
“Bacteria, Bile and Beyond” at RWTH Science Night (November 8th 2024) The outreach team of CRC1382 will have a booth at the 20th RWTH Science Night. RWTH Science Night has been attracting thousands of visitors every year since 2003, with a unique way of presenting science to the public in the late hours [...]
By Anne Eisele|2024-08-26T11:12:07+02:0026.08.2024|
"The Fast and the Furious" at Pint of Science 2024 Pint of Science brings scientists to share their research directly with the public in local cafes and pubs around the world. Pr. Grognot (Project A10) gave a talk entitled "The fast and the furious" at the first Pint of Science event in Aachen [...]
By Anne Eisele|2024-08-08T09:57:55+02:0008.08.2024|
New CRC publication in Liver International: Using machine learning and big data to understand the gut liver axis Metabolic dysfunction-associated steatotic liver disease (MASLD) affects approximately one third of the population and can progress to much more severe states of liver damage influenced by the interplay of lifestyle, genes and environment. One [...]
By Anne Eisele|2024-08-08T09:52:24+02:0009.07.2024|
New CRC publication in Advanced Science: Dissecting Acute Drug-Induced Hepatotoxicity and Therapeutic Responses of Steatotic Liver Disease Using Primary Mouse Liver and Blood Cells in a Liver-On-A-Chip Model Metabolic dysfunction-associated steatotic liver disease (MASLD) is a chronic liver disease affecting more than one quarter of humankind. This study by Adrien Guillot, Frank [...]
