Blood Endotoxin Levels as Biomarker of Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-analysis

By |2023-01-06T13:20:52+01:0006.01.2023|

New CRC publication:  Blood Endotoxin Levels as Biomarker of Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-analysis   This publication in Clinical Gastroenterology and Hepatology is the result of intensive collaboration of scientists in our CRC. Scientists from 5 CRC projects participated in this study: [...]

“Fazirsiran for Liver Disease Associated with Alpha1-Antitrypsin Deficiency”

By |2023-01-04T21:32:30+01:0022.11.2022|

New CRC publication:  Fazirsiran for Liver Disease Associated with Alpha1-Antitrypsin Deficiency   Promising results on a phase 2 clinical study entitled "Fazirsiran for Liver Disease Associated with Alpha1-Antitrypsin Deficiency" was recently published in The New England Journal of Medicine. Alpha1-antitrypsin deficiency is an inherited, proteotoxic disorder [...]

“Eggerthella lenta DSM 2243 Alleviates Bile Acid Stress Response in Clostridium ramosum and Anaerostipes caccae by Transformation of Bile Acids”

By |2023-01-04T21:29:15+01:0022.11.2022|

New CRC publication "Eggerthella lenta DSM 2243 Alleviates Bile Acid Stress Response in Clostridium ramosum and Anaerostipes caccae by Transformation of Bile Acids"   The recent publication in Microorganisms "Eggerthella lenta DSM 2243 Alleviates Bile Acid Stress Response in Clostridium ramosum and Anaerostipes caccae by Transformation [...]

Bile Salt and FGF19 Signaling in the Early Phase of Human Liver Regeneration

By |2021-09-29T15:05:52+02:0023.09.2021|

New CRC publication "Bile Salt and FGF19 Signaling in the Early Phase of Human Liver Regeneration"   A major aim of our CRC is to foster collaborations between the participating groups. The latest publication 'Bile Salt and FGF19 Signaling in the Early Phase of Human Liver [...]

The gut bacterium Extibacter muris produces secondary bile acids and influences liver physiology in gnotobiotic mice

By |2021-01-15T15:36:40+01:0015.01.2021|

New CRC publication "The gut bacterium Extibacter muris produces secondary bile acids and influences liver physiology in gnotobiotic mice" Barely two weeks have passed and we can already announce the next excellent article from our CRC consortium. In project A05, PIs Tom Clavel and Martin von Bergen together [...]

MAdCAM-1/α4β7 Integrin-Mediated Lymphocyte/Endothelium Interactions Exacerbate Acute Immune-Mediated Hepatitis in Mice

By |2021-01-06T17:11:40+01:0006.01.2021|

New CRC publication "MAdCAM-1/α4β7 Integrin-Mediated Lymphocyte/Endothelium Interactions Exacerbate Acute Immune-Mediated Hepatitis in Mice" Within CRC 1382 we encourage collaborations between different areas of research and disciplines. The result of such a joint venture is visible in the latest publication MAdCAM-1/a4b7 Integrin-Mediated Lymphocyte/Endothelium Interactions Exacerbate Acute Immune-Mediated Hepatitis in [...]

Uremic Toxins Affecting Cardiovascular Calcification: A Systematic Review

By |2020-11-12T22:55:30+01:0012.11.2020|

New CRC 1382 publication "Uremic Toxins Affecting Cardiovascular Calcification: A Systematic Review" Our CRC-members Heidi Noels and Joachim Jankowski (both A04) have written and contributed to a publication in Cells which is now available as open access paper. DOI: https://doi.org/10.3390/cells9112428 Further reading [...]

“Disturbed bile homeostasis and microbiota composition by intestinal protozoan infection causing metabolic dysregulation and growth impairment”

By |2020-10-15T12:11:41+02:0015.10.2020|

New CRC 1382 publication "Disturbed gut microbiota and bile homeostasis in Giardia-infected mice contributes to metabolic dysregulation and growth impairment" Our members Mathias W. Hornef (B01, Q03), Martin von Bergen (A05), Felix Gremse (Q01), Fabian Kiessling (Q01) and Christian Trautwein (A06, A08) have written and contributed [...]

“Rational design of a microbial consortium of mucosal sugar utilizers reduces Clostridiodes difficile colonization”

By |2020-10-14T09:05:53+02:0014.10.2020|

New CRC 1382 publication "Rational design of a microbial consortium of mucosal sugar utilizers reduces Clostridiodes difficile colonization" Our member Martin von Bergen, PI of project A05, was co-authoring a publication in Nature Communications which is now available as open access paper. Further reading [...]

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