CRC1382 Graduate school – Clinical rotation in Pathology started

By |2024-04-22T11:19:35+02:0022.04.2024|

CRC1382 Graduate School: new clinical rotation in pathology To further strengthen the translational aspect of the educational programme for the PhD students of the CRC1382 "Gut-Liver Axis" graduate school, a new tailored clinical rotation covering the field of Pathology could be offered to them. Next to a lecturing part where they learned [...]

Addressing the function of microbially conjugated bile salts in human bile

By |2024-03-25T16:24:58+01:0025.03.2024|

Publication in Hepatology Communications Microbially conjugated bile salts found in human bile activate the bile salt receptors TGR5 and FXR   Bile salts are an important means of communication in the organ crosstalk between gut and liver. PhD student Ümran Ay, Frank Schaap, Steven Olde Damink [...]

Salmonella infection – non-professional efferocytosis contributes to barrier integrity in the neonate

By |2024-02-07T17:04:40+01:0007.02.2024|

Publication in the Journal of Experimental Medicine Salmonella infection: Non-professional efferocytosis contributes to barrier integrity in the neonate   The immune system and the intestinal barrier of neonates and adult organisms are fundamentally different. Therefore, infections with the enteropathogen Salmonella have a different course and outcome [...]

Film show on Microbiota in Aachen Apollo Cinema moderated by CRC1382 PIs

By |2024-02-06T17:47:12+01:0006.02.2024|

“Our Microbiome – the invisible extinction“ - Special cinema screening with discussion, moderated by CRC1382 PIs Oliver Pabst and Tom Clavel   In the documentary "Our Microbiome - The Invisible Extinction", filmmakers Steven Lawrence and Sarah Schenck accompany the two microbiologists Gloria Dominguez-Bello and her husband, Martin Blaser who [...]

Graduate student highly successful at World Molecular Imaging Congress

By |2023-09-21T10:48:44+02:0021.09.2023|

CRC1382 graduate student highly successful at WMIC 2023 Sarah received multiple awards at WMIC 2023 in Prague In September 3rd year graduate student Sarah Schraven presented her work at the World Molecular Imaging Congress (WMIC) in Prague . Her presentation with the topic "CT-MRI-aided [...]

‘Gut–liver axis: barriers and functional circuits’ – Key findings and concepts of our CRC published in nature reviews gastrenterology & hepatology

By |2023-04-27T17:43:58+02:0027.04.2023|

nature reviews gastroenterology & hepatology:  'Gut-liver axis: barriers and functional circuits'   On behalf of our entire consortium, our spokesperson Oliver Pabst (B06, Q04), Mathias W. Hornef (B01, Q03), Frank Schaap (A07), Thomas Clavel (A05, Q02), Vuk Cerovic (B03) and Tony Bruns (B07) have summarised central [...]

‘Programmed and environmental determinants driving neonatal mucosal immune development’ – Publication in Immunity goes online on the first of May.

By |2023-04-27T17:41:45+02:0027.04.2023|

New CRC publication:  Programmed and environmental determinants driving neonatal mucosal immune development   Natalia Torow, one of our CRC1382 'Rising Stars' and PI Mathias Hornef (project B01) have published this review article in Immunity. 'In this paper we demonstrate that despite early microbial colonization the delayed [...]

Hepatology: Mapping the hepatic immune landscape identifies monocytic macrophages as key drivers of steatohepatitis and cholangiopathy progression

By |2023-04-27T16:40:44+02:0027.04.2023|

New CRC publication:  Mapping the hepatic immune landscape identifies monocytic macrophages as key drivers of steatohepatitis and cholangiopathy progression   PIs from external project B05 at Charité Berlin, Adrien Guillot as first author and Frank Tacke as last author, succeeded in publishing their results in the [...]

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